Bergeisen G H, Hinds M W, Skaggs J W
Am J Public Health. 1985 Feb;75(2):161-4. doi: 10.2105/ajph.75.2.161.
In November 1982, Meade County, Kentucky health officials noted a sudden increase in the incidence of hepatitis A. Using a standardized interview of 73 cases (68 serologically confirmed), and 85 controls (all negative for antibody to hepatitis A virus), the most important risk factor identified was household use of untreated water from a single spring. A dose-response relationship was found for consumption of unboiled spring water. Water samples taken from the spring during the outbreak were contaminated with fecal coliforms.
1982年11月,肯塔基州米德县的卫生官员注意到甲型肝炎发病率突然上升。通过对73例病例(68例血清学确诊)和85名对照者(甲型肝炎病毒抗体均为阴性)进行标准化访谈,确定的最重要风险因素是家庭使用来自单一泉水的未处理水。发现饮用未煮沸的泉水存在剂量反应关系。疫情爆发期间从该泉采集的水样被粪便大肠菌群污染。