Bowen G S, McCarthy M A
Am J Epidemiol. 1983 Jun;117(6):695-705. doi: 10.1093/oxfordjournals.aje.a113603.
In August-October 1980, a sudden increase occurred in the number of cases of jaundice reported among residents of a rural, agricultural section of Lancaster County, Pennsylvania. Investigation confirmed the cases as hepatitis A and showed that the outbreak was associated with consumption of water from a water fountain in a hardware store and water from the adjacent family home, both of which came from a well contaminated with feces. A total of 49 cases occurred from August 11 to October 21 in store customers, employees, family members, and persons visiting the family residence. Unusual features of the outbreak included an epidemic curve with two peaks, a very high attack rate in susceptibles at highest risk (greater than 90%), a high proportion of cases with jaundice (85%), absence of asymptomatic cases, and a high male to female ratio due to the makeup of the group at risk.
1980年8月至10月期间,宾夕法尼亚州兰开斯特县一个农业乡村地区的居民中报告的黄疸病例数量突然增加。调查证实这些病例为甲型肝炎,并表明此次疫情与一家五金店内饮水机的水以及相邻家庭住宅的水的饮用有关,这两处水源均来自一口被粪便污染的水井。8月11日至10月21日期间,共有49例病例发生在商店顾客、员工、家庭成员以及到访该家庭住所的人员中。此次疫情的异常特征包括:疫情曲线有两个高峰;处于最高风险的易感人群中发病率极高(超过90%);黄疸病例比例很高(85%);无无症状病例;以及由于高危人群的构成导致男性与女性比例很高。