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Selective killing of contaminating human fibroblasts in epithelial cultures derived from colorectal tumours using an anti Thy-1 antibody-ricin conjugate.

作者信息

Paraskeva C, Buckle B G, Thorpe P E

出版信息

Br J Cancer. 1985 Jan;51(1):131-4. doi: 10.1038/bjc.1985.19.

DOI:10.1038/bjc.1985.19
PMID:3966968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1976832/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b20/1976832/14d3ec31812b/brjcancer00099-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b20/1976832/b9c7de1f80ae/brjcancer00099-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b20/1976832/14d3ec31812b/brjcancer00099-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b20/1976832/b9c7de1f80ae/brjcancer00099-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b20/1976832/14d3ec31812b/brjcancer00099-0126-a.jpg

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4
Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.与蓖麻毒素连接的抗Thy 1.2单克隆抗体是一种有效的细胞类型特异性毒素。
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5483-6. doi: 10.1073/pnas.77.9.5483.
5
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Cell-specific cytotoxicity expressed by a conjugate of ricin and murine monoclonal antibody directed against thy 1.1 antigen.
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Front Cell Neurosci. 2014 Sep 5;8:257. doi: 10.3389/fncel.2014.00257. eCollection 2014.
2
Expression of the beta 7 integrin by human endothelial cells.人内皮细胞中β7整合素的表达。
Am J Pathol. 1996 Nov;149(5):1651-60.
3
Antibody-mediated targeting in the treatment and diagnosis of cancer: an overview.抗体介导的靶向作用在癌症治疗与诊断中的概述

本文引用的文献

1
THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.AKR胸腺抗原及其在白血病和神经组织中的分布。
J Exp Med. 1964 Sep 1;120(3):413-33. doi: 10.1084/jem.120.3.413.
2
Human thy-1: unusual localization and possible functional significance in lymphoid tissues.人类甲状腺-1:在淋巴组织中的异常定位及可能的功能意义。
J Immunol. 1981 Mar;126(3):843-50.
3
Purification of Thy-1-related glycoproteins from human brain and fibroblasts: comparisons between these molecules and murine glycoproteins carrying Thy-1.1 and Thy-1.2 antigens.
Cancer Chemother Pharmacol. 1986;17(3):197-208. doi: 10.1007/BF00256685.
4
The isolation and description of LIF-10: a human tumor cell line derived from a colorectal adenocarcinoma.LIF-10的分离与描述:一种源自大肠腺癌的人类肿瘤细胞系
In Vitro Cell Dev Biol. 1990 Aug;26(8):743-5. doi: 10.1007/BF02623614.
从人脑中纯化与Thy-1相关的糖蛋白以及从成纤维细胞中纯化该糖蛋白:这些分子与携带Thy-1.1和Thy-1.2抗原的鼠糖蛋白之间的比较
Eur J Immunol. 1981 Aug;11(8):597-603. doi: 10.1002/eji.1830110802.
4
The preparation and cytotoxic properties of antibody-toxin conjugates.抗体-毒素偶联物的制备及其细胞毒性特性
Immunol Rev. 1982;62:119-58. doi: 10.1111/j.1600-065x.1982.tb00392.x.
5
Selective culture of epithelioid cells from a human squamous carcinoma using a monoclonal antibody to kill fibroblasts.使用单克隆抗体杀死成纤维细胞,从人鳞状细胞癌中选择性培养上皮样细胞。
Cell Biol Int Rep. 1980 Oct;4(10):917-22. doi: 10.1016/0309-1651(80)90193-9.
6
The isolation and characterization of colorectal epithelial cell lines at different stages in malignant transformation from familial polyposis coli patients.从家族性结肠息肉病患者中分离并鉴定处于恶性转化不同阶段的结肠上皮细胞系。
Int J Cancer. 1984 Jul 15;34(1):49-56. doi: 10.1002/ijc.2910340109.
7
The membrane antigens of human colorectal cancer cells: demonstration with monoclonal antibodies of heterogeneity within and between tumours and of anomalous expression of HLA-DR.人结肠癌细胞的膜抗原:用单克隆抗体证明肿瘤内部和肿瘤之间的异质性以及HLA-DR的异常表达。
Eur J Cancer Clin Oncol. 1983 Feb;19(2):209-20. doi: 10.1016/0277-5379(83)90419-4.
8
Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.用人白细胞共同抗原的一种主要为B淋巴细胞特异性决定簇的单克隆抗体进行鉴定。人白细胞共同分子结构和可能功能多样性的证据。
J Exp Med. 1981 Apr 1;153(4):753-65. doi: 10.1084/jem.153.4.753.
9
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.人表皮角质形成细胞系的连续培养:从单细胞形成角质化集落。
Cell. 1975 Nov;6(3):331-43. doi: 10.1016/s0092-8674(75)80001-8.
10
D-valine as a selective agent for normal human and rodent epithelial cells in culture.D-缬氨酸作为培养的正常人及啮齿动物上皮细胞的选择剂。
Cell. 1975 May;5(1):11-7. doi: 10.1016/0092-8674(75)90086-0.