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探索太空人类生殖的概念:未来研究的一个潜在领域。

Exploring the Idea of Human Reproduction in Space: A Potential Area for Future Research.

作者信息

Sharma Priyanka, Malik Sunita, Sarkar Avir

机构信息

Obstetrics and Gynecology, Employees' State Insurance Corporation (ESIC) Medical College and Hospital, Faridabad, Faridabad, IND.

出版信息

Cureus. 2024 Nov 14;16(11):e73712. doi: 10.7759/cureus.73712. eCollection 2024 Nov.

DOI:10.7759/cureus.73712
PMID:39677198
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11646162/
Abstract

As space travel evolves from brief missions to longer expeditions, and with the rise of space tourism, there is increasing interest in understanding how space travel affects human reproductive physiology and the feasibility of procreation in space. Space travel presents various potential hazards to reproductive health such as exposure to ionizing radiation, exposure to changes in gravity, psychological stress, and disruptions to the endocrine and urogenital systems, as well as the circadian rhythm. This article explores how cosmic radiation and microgravity impact both female and male gametogenesis, embryogenesis, and reproductive physiology.

摘要

随着太空旅行从短期任务发展到长期探险,以及太空旅游的兴起,人们越来越有兴趣了解太空旅行如何影响人类生殖生理以及在太空中生育的可行性。太空旅行对生殖健康存在各种潜在危害,例如暴露于电离辐射、重力变化、心理压力以及对内分泌和泌尿生殖系统以及昼夜节律的干扰。本文探讨了宇宙辐射和微重力如何影响女性和男性的配子发生、胚胎发生和生殖生理。

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本文引用的文献

1
Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells.模拟微重力通过破坏卵泡细胞间的通讯降低卵巢卵泡和卵母细胞的质量。
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The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model.微重力对抗癌症:多细胞球体作为转移模型。
Int J Mol Sci. 2022 Mar 12;23(6):3073. doi: 10.3390/ijms23063073.
3
Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression.国际空间站太空飞行对小鼠发情周期和卵巢基因表达的影响。
NPJ Microgravity. 2021 Mar 12;7(1):11. doi: 10.1038/s41526-021-00139-7.
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Survival Pathways Are Differently Affected by Microgravity in Normal and Cancerous Breast Cells.正常和癌细胞中的微重力对生存途径的影响不同。
Int J Mol Sci. 2021 Jan 16;22(2):862. doi: 10.3390/ijms22020862.
5
The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells.微重力对干细胞和肿瘤干细胞分化和细胞生长的影响。
Stem Cells Transl Med. 2020 Aug;9(8):882-894. doi: 10.1002/sctm.20-0084. Epub 2020 Apr 30.
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Medically induced amenorrhea in female astronauts.女性宇航员的药物性闭经
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Comparative proteomics reveals the underlying toxicological mechanism of low sperm motility induced by iron ion radiation in mice.比较蛋白质组学揭示铁离子辐射诱导小鼠精子活力低下的潜在毒理学机制。
Reprod Toxicol. 2016 Oct;65:148-158. doi: 10.1016/j.reprotox.2016.07.014. Epub 2016 Jul 25.
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Ann ICRP. 2013 Aug;42(4):1-339. doi: 10.1016/j.icrp.2013.05.004.