Rao Sitara, Ahmed Moeed, Ahmed Abdul R, Brown Julia
Department of Medicine, University of Illinois Chicago, Chicago, USA.
Department of Nephrology, Jesse Brown Department of Veterans Affairs Medical Center, Chicago, USA.
Cureus. 2024 Nov 14;16(11):e73703. doi: 10.7759/cureus.73703. eCollection 2024 Nov.
Pauci-immune glomerulonephritis is a rapidly progressive form of glomerulonephritis. It is distinguished from other rapidly progressive glomerular diseases by the lack of immune deposits seen on renal biopsy, hence the name "pauci-immune." We present a case of pauci-immune glomerulonephritis in a patient with a history of malignancy that was treated with chemotherapy. Notably, the presentation of kidney injury coincided with the discovery of a new metastasis. Prompt treatment of glomerulonephritis is critically important to preserve renal function, though the optimal treatment strategy may not be straightforward in a patient with coexisting malignancy. Ultimately, this case illustrates that collaboration between patients, medical teams, and families is needed to optimize treatment strategy in unique circumstances.
寡免疫性肾小球肾炎是一种快速进展型的肾小球肾炎。它与其他快速进展性肾小球疾病的区别在于肾活检时未见免疫沉积物，因此得名“寡免疫性”。我们报告一例有恶性肿瘤病史且接受过化疗的患者发生寡免疫性肾小球肾炎的病例。值得注意的是，肾损伤的表现与新转移灶的发现同时出现。及时治疗肾小球肾炎对于保护肾功能至关重要，尽管在合并恶性肿瘤的患者中，最佳治疗策略可能并非一目了然。最终，该病例表明在特殊情况下，患者、医疗团队和家庭之间需要合作以优化治疗策略。
