Graninger W, Pirich K, Derfler K, Waldhäusl W
J Clin Pathol. 1985 Jan;38(1):64-7. doi: 10.1136/jcp.38.1.64.
Plasma fibronectin concentrations up to 85 mg/100 ml were found in hyperthyroid patients. There was a significant correlation between free thyroxine index and plasma fibronectin values. Hypothyroid patients had low to normal fibronectin concentrations. Parallel decreases of thyroid hormones and plasma fibronectin concentrations were noted during treatment with thiamazole. A direct effect of thyroid hormones on fibronectin synthesis seems probable.
在甲状腺功能亢进患者中发现血浆纤连蛋白浓度高达85毫克/100毫升。游离甲状腺素指数与血浆纤连蛋白值之间存在显著相关性。甲状腺功能减退患者的纤连蛋白浓度低至正常。在使用甲巯咪唑治疗期间,观察到甲状腺激素和血浆纤连蛋白浓度平行下降。甲状腺激素对纤连蛋白合成可能有直接作用。