Schäfer-Somi Sabine, Lechner Dominik, Tichy Alexander, Spergser Joachim
Clinical Center for Reproduction, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Institute for Bioinformatics and Biostatistics, University of Veterinary Medicine Vienna, 1210 Vienna, Austria.
Animals (Basel). 2024 Nov 29;14(23):3460. doi: 10.3390/ani14233460.
The evaluation of canine vaginal bacteria during proestrus and estrus and the chosen parameters will help to prevent the misuse of antibiotics in veterinary medicine.
This study carried out a retrospective analysis to obtain microbiological examination results for vaginal swabs from 696 healthy dogs, all of whom were patients from one clinic. Age, body weight, fur length (long or short hair), the time of sampling of vaginal swabs, the duration of proestrus/estrus, progesterone (P4) concentration (the first and last samples), and bacteriological findings were evaluated.
Only 3.7% (26/696) of the samples were negative for bacteria. The impact of fur length was low. However, the calculation of the odds ratios revealed that the chance for a high-grade growth of () and () increases with body weight class. The earlier the sampling was performed, the lower the number of high-grade cultures ( < 0.01). The duration between the first and last measurement of progesterone (P4) was positively related to the cultural detection of , spp., and spp. ( < 0.05) and negatively to the cultivation of spp. ( < 0.01).
Our findings reflect some likely factors contributing to the variability of the physiological vaginal flora in dogs, which may help interpret cultured bacteriological findings.
评估犬在发情前期和发情期的阴道细菌以及所选参数将有助于防止兽医学中抗生素的滥用。
本研究进行了一项回顾性分析，以获取来自696只健康犬的阴道拭子的微生物学检查结果，所有这些犬均为一家诊所的患者。对年龄、体重、毛长（长毛或短毛）、阴道拭子采样时间、发情前期/发情期持续时间、孕酮（P4）浓度（首次和末次样本）以及细菌学检查结果进行了评估。
仅3.7%（26/696）的样本细菌检测为阴性。毛长的影响较小。然而，比值比的计算表明，随着体重等级的增加，（）和（）高度生长的可能性增加。采样时间越早，高度培养物的数量越低（<0.01）。首次和末次孕酮（P4）测量之间的持续时间与、 spp.和 spp.的培养检测呈正相关（<0.05），与 spp.的培养呈负相关（<0.01）。
我们的研究结果反映了一些可能导致犬生理性阴道菌群变异的因素，这可能有助于解释培养的细菌学检查结果。
