Channabasavana Hundi Puttaningaiah Keshavananda Prabhu
School of Chemical, Biological, and Battery Engineering, Gachon University, Gyeonggi-do, Seongnam-si 13120, Republic of Korea.
Nanomaterials (Basel). 2024 Nov 25;14(23):1890. doi: 10.3390/nano14231890.
Electrochemical biosensors have emerged as predominant devices for sensitive, rapid, and specific sensing of biomolecules, with significant applications in clinical diagnostics, environmental observation, and food processing. The improvement of inventive materials, especially carbon-based materials, and metal/metal oxide nanoparticles (M/MONPs), has changed the impact of biosensing, improving the performance and flexibility of electrochemical biosensors. Carbon-based materials, such as graphene, carbon nanotubes, and carbon nanofibers, have excellent electrical conductivity, a high surface area, large pore size, and good biocompatibility, making them ideal electrocatalysts for biosensor applications. Furthermore, M and MONPs have highly effective synergistic, electronic, and optical properties that influence signal transduction, selectivity, and sensitivity. This study completely explored continuous progressions and upgrades in carbonaceous materials (CBN materials) and M/MONPs for electrochemical biosensor applications. It analyzed the synergistic effects of hybrid nanocomposites that combine carbon materials with metal nanoparticles (MNPs) and their part in upgrading sensor performance. The paper likewise incorporated the surface alteration procedures and integration of these materials into biosensor models. The study examined difficulties, requirements, and possibilities for executing these innovative materials in practical contexts. This overview aimed to provide specialists with insights into the most recent patterns in the materials study of electrochemical biosensors and advance further progressions in this dynamic sector.
电化学生物传感器已成为用于灵敏、快速且特异性检测生物分子的主要器件，在临床诊断、环境监测和食品加工等领域有重要应用。创新材料的改进，尤其是碳基材料和金属/金属氧化物纳米颗粒（M/MONPs），改变了生物传感的影响，提高了电化学生物传感器的性能和灵活性。碳基材料，如石墨烯、碳纳米管和碳纳米纤维，具有优异的导电性、高表面积、大孔径和良好的生物相容性，使其成为生物传感器应用的理想电催化剂。此外，M和MONPs具有高效的协同、电子和光学性质，可影响信号转导、选择性和灵敏度。本研究全面探讨了用于电化学生物传感器应用的含碳材料（CBN材料）和M/MONPs的持续进展与升级。分析了将碳材料与金属纳米颗粒（MNPs）结合的混合纳米复合材料的协同效应及其在提升传感器性能中的作用。论文还纳入了这些材料的表面改性方法以及将其集成到生物传感器模型中的情况。该研究考察了在实际环境中应用这些创新材料的困难、要求和可能性。本综述旨在为专家提供有关电化学生物传感器材料研究最新趋势的见解，并推动这一动态领域的进一步发展。
