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亚洲肌少症工作组(AWGS-2019)定义的泰国社区居住老年人肌少症的流行率和危险因素:一项横断面研究。

The prevalence and risk factors of sarcopenia among Thai community-dwelling older adults as defined by the Asian Working Group for Sarcopenia (AWGS-2019) criteria: a cross-sectional study.

机构信息

Geriatric Emergency Medicine Unit, The Department of Emergency Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.

Department of Rehabilitation, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.

出版信息

BMC Geriatr. 2022 Oct 7;22(1):786. doi: 10.1186/s12877-022-03471-z.

Abstract

BACKGROUND

This study aimed to determine the prevalence and risk factors for sarcopenia and severe sarcopenia among urban community-dwelling adults in Thailand, using the Asian Working Group for Sarcopenia (AWGS-2019) criteria.

METHODS

This cross-sectional study comprising 892 older adults aged > 60 years analyzed data from a cohort study (Bangkok Falls study; 2019-2021). The appendicular skeletal muscle mass was evaluated using the Bioelectrical Impedance Analysis (BIA) method. Physical performance and muscle strength were evaluated using the five-time sit-to-stand and handgrip strength tests, respectively. Logistic regression was used to determine the factors associated with sarcopenia.

RESULTS

The prevalence rates of sarcopenia and severe sarcopenia were 22.2% and 9.4%, respectively. Age ≥ 70 years (adjusted odds ratio (aOR), 2.40; 95% confidence interval (CI), 1.67-3.45), body mass index (BMI) of < 18.5 kg/m (aOR, 8.79; 95% CI, 4.44-17.39), Mini Nutritional Assessment (MNA) score of < 24 (aOR, 1.75; 95% CI, 1.24-2.48), and a six-item cognitive screening test score of ≥ 8 (aOR, 1.52; 95% CI, 1.08-12.15) were associated with sarcopenia. Likewise, age ≥ 70 years, BMI < 18.5 kg/m, and an MNA score of < 24 predicted severe sarcopenia.

CONCLUSION

One-third of the urban community-dwelling older Thai adults had sarcopenia or severe sarcopenia. The age ≥ 70 years, low BMI, and inadequate nutrition increased the risk of both sarcopenia and severe sarcopenia while impaired cognitive functions predicted only sarcopenia in this population.

摘要

背景

本研究旨在使用亚洲肌少症工作组(AWGS-2019)标准,确定泰国城市社区居住的成年人中肌少症和严重肌少症的患病率和危险因素。

方法

本横断面研究纳入了 892 名年龄大于 60 岁的老年人,分析了来自队列研究(曼谷跌倒研究;2019-2021 年)的数据。使用生物电阻抗分析法(BIA)评估四肢骨骼肌质量。使用五次坐站和握力测试分别评估身体机能和肌肉力量。使用逻辑回归确定与肌少症相关的因素。

结果

肌少症和严重肌少症的患病率分别为 22.2%和 9.4%。年龄≥70 岁(调整后的优势比(aOR),2.40;95%置信区间(CI),1.67-3.45)、BMI<18.5kg/m(aOR,8.79;95%CI,4.44-17.39)、微型营养评估(MNA)评分<24(aOR,1.75;95%CI,1.24-2.48)和六项认知筛查测试评分≥8(aOR,1.52;95%CI,1.08-12.15)与肌少症相关。同样,年龄≥70 岁、BMI<18.5kg/m 和 MNA 评分<24 预测严重肌少症。

结论

三分之一的泰国城市社区居住的老年成年人患有肌少症或严重肌少症。年龄≥70 岁、低 BMI 和营养不足增加了肌少症和严重肌少症的风险,而认知功能受损仅预测该人群的肌少症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40ff/9540717/a715ccfd047b/12877_2022_3471_Fig1_HTML.jpg

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