Sharma Yash, Kannan Ajith, Lee James M, Coffman Frederick, Mittal Rahul
Health Informatics, Rutgers University, Piscataway, USA.
Orthopaedic Surgery, Orange Orthopaedic Associates, West Orange, USA.
Cureus. 2024 Nov 16;16(11):e73806. doi: 10.7759/cureus.73806. eCollection 2024 Nov.
The discovery of insulin by Frederick G Banting and his colleagues in 1921 marked a pivotal moment in medical history. Born in Ontario, Canada, in 1891, Banting's childhood was impacted by the death of his closest friend, Jane, who died of diabetes mellitus at a young age. This personal tragedy profoundly influenced him to choose a career in medicine and fueled his determination to find a cure for diabetes. This journey led to the discovery of Insulin with the help of Charles H Best and John JR Macleod, resulting in a Nobel Prize for this work. Their discoveries set the stage for advancements in clinical medicine and biotechnology, including developing recombinant insulin over 50 years later.
1921年，弗雷德里克·G·班廷及其同事发现了胰岛素，这标志着医学史上的一个关键时刻。班廷于1891年出生在加拿大安大略省，他的童年因挚友简的离世而受到影响，简年少时死于糖尿病。这场个人悲剧深刻地影响了他选择医学事业，并激发了他寻找糖尿病治疗方法的决心。在查尔斯·H·贝斯特和约翰·JR·麦克劳德的帮助下，他踏上了这段旅程，最终发现了胰岛素，并因此获得了诺贝尔奖。他们的发现为临床医学和生物技术的进步奠定了基础，包括50多年后开发出重组胰岛素。
