Etehadtavakol Mahnaz, Shokrani Parvaneh, Shanei Ahmad
Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Med Signals Sens. 2024 Nov 5;14:30. doi: 10.4103/jmss.jmss_49_23. eCollection 2024.
Proton therapy is a cancer treatment method that uses high-energy proton beams to target and destroy cancer cells. In recent years, the use of proton therapy in cancer treatment has increased due to its advantages over traditional radiation methods, such as higher accuracy and reduced damage to healthy tissues. For accurate planning and delivery of proton therapy, advanced software tools are needed to model and simulate the interaction between the proton beam and the patient's body. One of these tools is the Monte Carlo simulation software called Geant4, which provides accurate modeling of physical processes during radiation therapy. The purpose of this study is to investigate the effectiveness of the Geant4 toolbox in proton therapy in the conducted research. This review article searched for published articles between 2002 and 2023 in reputable international databases including Scopus, PubMed, Scholar, Google Web of Science, and ScienceDirect. Geant4 simulations are reliable and accurate and can be used to optimize and evaluate the performance of proton therapy systems. Obtaining some data from experiments carried out in the real world is very effective. This makes it easy to know how close the values obtained from simulations are to the behavior of ions in reality.
质子治疗是一种癌症治疗方法，它使用高能质子束来靶向和摧毁癌细胞。近年来，质子治疗在癌症治疗中的应用有所增加，因为它相对于传统放射方法具有优势，例如更高的准确性和对健康组织的损伤更小。为了精确规划和实施质子治疗，需要先进的软件工具来模拟质子束与患者身体之间的相互作用。其中一种工具是名为Geant4的蒙特卡罗模拟软件，它能对放射治疗期间的物理过程进行精确建模。本研究的目的是在已开展的研究中调查Geant4工具箱在质子治疗中的有效性。这篇综述文章在包括Scopus、PubMed、Scholar、谷歌学术搜索和ScienceDirect在内的知名国际数据库中搜索了2002年至2023年期间发表的文章。Geant4模拟是可靠且准确的，可用于优化和评估质子治疗系统的性能。从现实世界中进行的实验获取一些数据非常有效。这使得很容易了解从模拟中获得的值与离子在现实中的行为有多接近。
