Institute of Experimental Ophthalmology, Saarland University, Homburg, Germany.
Department of Optometry, Ernst Abbe University of Applied Sciences, Jena, Germany.
BMJ Open Ophthalmol. 2022 Apr 5;7(1):e000971. doi: 10.1136/bmjophth-2022-000971. eCollection 2022.
Visual performance and short-term tolerability of different designs of myopia correcting options, including therapeutically relevant bifocal contact lenses (CL) and spectacle lenses with 'defocus incorporated multiple segments (DIMS)' technology were compared.
In myopic volunteering subjects (n=8; spherical equivalent range: -1 to -7 D) visual acuity (VA) using Landolt C and contrast sensitivity (CS) using contrast C were assessed at three different gaze positions (-22° nasal, +22° temporal and 0° central), corresponding to a gaze through the DIMS area or the clear area of the DIMS lens design, respectively, after short-term wear of each of single vision spectacle lenses (SV), DIMS spectacle lenses (DIMS), monofocal soft CL and centre-near multifocal soft CL (MCL). Also, CS was assessed under photopic and mesopic light conditions with and without glare using sinusoidal gratings at 1.5, 3, 6, 12 and 18 cpd.
Mean VA (Landolt C) was -0.12 to -0.10, -0.05 and 0.10 logMAR (SV, DIMS, CL, MCL) at central gaze (0°). At nasal gaze (-22°), VA differed by 0.12, 0.33, 0.05 and 0.01, and at temporal gaze (+22°) by 0.05, 0.26, 0 and -0.08 compared with central gaze values. Mean CS (Contrast C) was 1.74, 1.73, 1.69 and 1.61 logCS (SV, DIMS, CL, MCL) at central gaze at nasal gaze, CS differed by -0.02 to -0.13, -0.01 and -0.01, and at temporal gaze by -0.02 to -0.16, -0.01 and +0.06 compared with central gaze values.
When compared with SV, MCL leads to a general decrease in VA and CS, while DIMS did not differ from SV at straight gaze (0° gaze). With DIMS, VA and CS are decreased to a similar level as with the MCL, but only at nasal and temporal gaze.
比较不同设计的近视矫正方案的视觉性能和短期耐受性，包括治疗相关的双焦点接触镜（CL）和具有“离焦多焦点（DIMS）”技术的眼镜。
在近视志愿者受试者（等效球镜范围：-1 至-7D）中，在三种不同注视位置（-22°鼻侧、+22°颞侧和 0°中央）下评估使用 Landolt C 的视力（VA）和使用对比度 C 的对比敏感度（CS），分别对应于通过 DIMS 区域或 DIMS 镜片设计的清晰区域注视时的情况，分别在短期佩戴单视眼镜（SV）、DIMS 眼镜（DIMS）、单焦点软 CL 和中心-近多焦点软 CL（MCL）后进行。此外，在明视和中间视觉光条件下，使用正弦光栅在 1.5、3、6、12 和 18 cpd 下评估有和没有眩光的 CS。
在中央注视（0°）时，平均 VA（Landolt C）为-0.12 至-0.10、-0.05 和 0.10 logMAR（SV、DIMS、CL、MCL）。在鼻侧注视（-22°）时，VA 分别相差 0.12、0.33、0.05 和 0.01，在颞侧注视（+22°）时，VA 分别相差 0.05、0.26、0 和-0.08。在中央注视时，平均 CS（Contrast C）为 1.74、1.73、1.69 和 1.61 logCS（SV、DIMS、CL、MCL），在鼻侧注视时 CS 相差-0.02 至-0.13、-0.01 和-0.01，在颞侧注视时 CS 相差-0.02 至-0.16、-0.01 和+0.06。
与 SV 相比，MCL 导致 VA 和 CS 普遍下降，而 DIMS 在直视（0°注视）时与 SV 没有差异。使用 DIMS 时，VA 和 CS 下降到与 MCL 相似的水平，但仅在鼻侧和颞侧注视时。
