Deng Kexin, Fan Xiaofei, Yuan Zhigen, Li Dian
Department of Orthopaedics, The Second People's Hospital of Hunan Province (Brain Hospital of Hunan Province), Changsha, Hunan, China.
Department of Plastic and Reconstruction, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Front Microbiol. 2024 Dec 3;15:1453755. doi: 10.3389/fmicb.2024.1453755. eCollection 2024.
Bacteria play a crucial role in maintaining the health of human skin. Research has demonstrated that probiotics present notable benefits for extraintestinal organs. Despite the extensive research on the impact of probiotics on skin health, there is a notable absence of regulatory frameworks governing their external application, with no approval from the FDA for any probiotic products for external use. The aim of this study is to offer a thorough summary of the research status in the field since 2000 and project future trends.
The Web of Science Core Collection and SCI-Expanded index were selected for an extensive search of studies concerning the role of probiotics in skin health since 2000. A total of 1,306 publications were identified. Employing a double-blind method, two subsets of literature were scrutinized and subsequently combined for analysis. Using CiteSpace, this research explored key aspects such as primary countries, institutions, authors, journals, trending topics, research frontiers, and emerging patterns in research related to application of probiotic for skin health.
This article included 709 research papers. The number of published papers has shown a rapid increase. The United States had the highest number of research papers (128), and Canada had the highest intermediate centrality (0.23). The University of California System emerged as the most prolific institution. Huang, Chun-Ming has published the most articles, and his research is at the forefront among those prolific authors. Twelve clusters were identified, with cluster #0 skin microbiota, #3 mechanisms, and #8 antimicrobial being the most recent. As for the hot topic, "diversity," "health," "skin microbiome," "oxidative stress," "microbiota," and "antioxidants" have been at the forefront of the current field. The overall research trend has shifted from clinical trials to mechanistic exploration and from oral treatments to external applications, with the research level moving from general categories to specific strains.
This paper summarized and visualized academic achievements in the field of probiotic application for skin health using CiteSpace and VOSviewer, offering a systematic and comprehensive perspective, along with a longitudinal overview of this research field.
细菌在维持人体皮肤健康方面发挥着关键作用。研究表明，益生菌对肠外器官具有显著益处。尽管对益生菌对皮肤健康的影响进行了广泛研究，但在其外用方面明显缺乏监管框架，美国食品药品监督管理局（FDA）尚未批准任何外用益生菌产品。本研究旨在全面总结2000年以来该领域的研究现状并预测未来趋势。
选择科学网核心合集和SCI扩展索引，对2000年以来有关益生菌在皮肤健康中作用的研究进行广泛检索。共识别出1306篇出版物。采用双盲法，对两个文献子集进行审查，随后合并进行分析。本研究使用CiteSpace探索了与益生菌用于皮肤健康相关研究的主要国家、机构、作者、期刊、热门话题、研究前沿和新兴模式等关键方面。
本文纳入709篇研究论文。发表论文数量呈快速增长趋势。美国的研究论文数量最多（128篇），加拿大的中间中心性最高（0.23）。加利福尼亚大学系统是发文量最多的机构。黄春明发表的文章最多，在高产作者中其研究处于前沿地位。识别出12个聚类，其中聚类#0皮肤微生物群、#3机制和#8抗菌是最新的。至于热门话题，“多样性”“健康”“皮肤微生物组”“氧化应激”“微生物群”和“抗氧化剂”一直处于当前领域的前沿。总体研究趋势已从临床试验转向机制探索，从口服治疗转向外用，研究水平从一般类别转向特定菌株。
本文使用CiteSpace和VOSviewer总结并可视化了益生菌用于皮肤健康领域的学术成果，提供了系统全面的视角以及该研究领域的纵向概述。
