Griffith R B, Hancock R
Toxicology. 1985 Feb;34(2):123-38. doi: 10.1016/0300-483x(85)90162-3.
Equipment and procedures for the simultaneous exposure of cell cultures and rodents to mainstream and sidestream smoke are described. Whole smoke or the gas phase of smoke can be generated and manipulated under a wide range of conditions. Identical smoke can be used for the exposure of cell cultures, perfused lungs, and for the exposure of experimental animals. The equipment is relatively inexpensive, and can be used by a small laboratory for efficient, controlled smoke exposure studies. Total particulate matter data are used to illustrate the flexibility of smoke generation, manipulation, and dose variables which can be obtained with the exposure systems.
描述了将细胞培养物和啮齿动物同时暴露于主流和侧流烟雾的设备和程序。可以在广泛的条件下产生和控制全烟雾或烟雾气相。相同的烟雾可用于细胞培养物、灌注肺的暴露以及实验动物的暴露。该设备相对便宜，小型实验室即可使用，用于高效、可控的烟雾暴露研究。总颗粒物数据用于说明使用暴露系统可获得的烟雾生成、控制和剂量变量的灵活性。
