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一名年轻男性的巨大囊性肺细胞瘤:具有临床放射学和组织病理学特征的罕见诊断难题

Giant Cystic Pneumocytoma in a Young Male: Rare Diagnostic Conundrum with Clinicoradiological and Histopathological Features.

作者信息

Singhal Manphool, Yadav Nishita, Subramanian Pavithra, Singh Harkant, Bal Amanjit, Sharma Arun

机构信息

Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Cardiovascular & Thoracic Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Radiol Imaging. 2024 Aug 26;35(1):192-195. doi: 10.1055/s-0044-1789244. eCollection 2025 Jan.

Abstract

Pulmonary sclerosing pneumocytoma is a rare benign neoplasm typically seen in middle-aged women. The exact preoperative diagnosis is quite challenging considering its nonspecific clinical and radiologic features along with complex histology. Moreover, obtaining an exact histopathological diagnosis can be difficult especially with the small biopsy specimens. Most patients are generally asymptomatic with incidental detection of peripheral, homogenous, solitary pulmonary nodule. It is essential to differentiate it from other mimickers including malignant lesions as limited surgical resection is curative in these cases without adjuvant therapy. We present a rare giant cystic variant of pneumocytoma, in a young male, which was initially mimicking inflammatory myofibroblastic tumor even on preoperative histology.

摘要

肺硬化性细胞瘤是一种罕见的良性肿瘤,多见于中年女性。鉴于其非特异性的临床和影像学特征以及复杂的组织学表现,术前准确诊断颇具挑战性。此外,尤其是对于小活检标本,获得准确的组织病理学诊断可能很困难。大多数患者通常无症状,多通过偶然发现外周均匀的孤立性肺结节。将其与包括恶性病变在内的其他类似疾病相鉴别至关重要,因为在这些病例中,有限的手术切除即可治愈,无需辅助治疗。我们报告了一例罕见的男性青年肺硬化性细胞瘤巨大囊性变体病例,即使在术前组织学检查中,该病例最初也被误诊为炎性肌纤维母细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9259/11651875/4eff8b88de10/10-1055-s-0044-1789244-i2443562-1.jpg

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