Li Zhengliang, Zheng Chanjuan, Zhang Wei, Zhang Xueyi, Duan Can, Sun Xi, Xia Wenguang
College of Chinese Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Xinhua Hospital of Hubei University of Chinese Medicine, Hubei Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Wuhan, China.
BMC Musculoskelet Disord. 2024 Dec 19;25(1):1020. doi: 10.1186/s12891-024-08128-z.
Using the data taken from the National Health and Nutrition Examination Survey (NHANES) database, we explored the relationship between the dietary inflammatory index (DII) and low muscle mass (LMM) in adults.
We examined 20,424 adults ≥ 20 years old from the 1999-2006 and 2011-2018 NHANES. We hypothesized that the DII is positively associated with the risk of LMM in adults. Regression, subgroup, and restricted cubic spline (RCS) analyses were used to determine the association between the DII and the risk of LMM.
Analyzing the DII as a continuous variable revealed that each unit increase in DII was associated with an 11% increase in the risk of LMM. When categorized by quartile grouping, the analysis indicated that individuals in the highest DII quartile exhibited a 1.78-fold higher risk of LMM compared to those in the lowest quartile (OR = 1.78, 95% CI: 1.45-2.18). The RCS analysis demonstrated that the risk of LMM remained stable for DII below 1.77, but increased sharply for DII of 1.77 or higher. Subgroup analysis further revealed that the impact of DII on LMM risk was more pronounced in individuals with a body mass index (BMI) of 25 kg/m or greater.
It is necessary to adjust the diet according to the DII to reduce the possibility of LMM and to prevent the occurrence of sarcopenia.
利用从美国国家健康与营养检查调查（NHANES）数据库获取的数据，我们探讨了成年人饮食炎症指数（DII）与低肌肉量（LMM）之间的关系。
我们研究了来自1999 - 2006年和2011 - 2018年NHANES的20424名年龄≥20岁的成年人。我们假设DII与成年人LMM风险呈正相关。采用回归分析、亚组分析和受限立方样条（RCS）分析来确定DII与LMM风险之间的关联。
将DII作为连续变量进行分析发现，DII每增加一个单位，LMM风险增加11%。按四分位数分组进行分析时，结果表明，DII最高四分位数组的个体发生LMM的风险比最低四分位数组的个体高1.78倍（OR = 1.78，95%CI：1.45 - 2.18）。RCS分析表明，DII低于1.77时，LMM风险保持稳定，但DII为1.77及以上时风险急剧增加。亚组分析进一步显示，DII对LMM风险的影响在体重指数（BMI）为25kg/m²或更高的个体中更为明显。
有必要根据DII调整饮食，以降低发生LMM的可能性，并预防肌肉减少症的发生。
