病毒组组装揭示了从一份儿科支气管肺泡灌洗样本中分离出的本地假单胞菌噬菌体的基因组草图。
Virome assembly reveals draft genomes of native Pseudomonas phages isolated from a paediatric bronchoalveolar lavage sample.
作者信息
Agudelo-Romero Patricia, Caparros-Martin Jose A, Sharma Abhinav, Saladié Montserrat, Sly Peter D, Stick Stephen M, O'Gara Fergal
机构信息
Wal-Yan Respiratory Research Centre, Telethon Kids Institute, Perth, Western Australia, Australia.
Australian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.
出版信息
Microbiol Resour Announc. 2025 Feb 11;14(2):e0103024. doi: 10.1128/mra.01030-24. Epub 2024 Dec 20.
Abstract
We present lung virome data recovered through shotgun metagenomics in bronchoalveolar lavage fluid from an infant with cystic fibrosis, who tested positive for infection. Using a bioinformatic pipeline for virus characterization in shotgun metagenomic data, we identified five viral contigs representing Pseudomonas phages classified as Caudoviricetes.
摘要
我们展示了通过鸟枪法宏基因组学从一名囊性纤维化婴儿的支气管肺泡灌洗流体中获得的肺部病毒组数据，该婴儿感染检测呈阳性。利用一种用于在鸟枪法宏基因组数据中进行病毒特征鉴定的生物信息学流程，我们鉴定出了五条代表被归类为有尾噬菌体目的假单胞菌噬菌体的病毒重叠群。
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本文引用的文献
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注：这里“Bronchoalveolar Lavage Fluid”准确的中文是“支气管肺泡灌洗液”，原译文“fluid”未翻译完整。完整译文如下：
低丰度呼吸道生物量样本的微生物组分析；提高支气管肺泡灌洗液中微生物 DNA 的回收率 。
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