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一种用于生物组织无创动态成像的可穿戴摩擦电阻抗断层扫描系统。

A wearable triboelectric impedance tomography system for noninvasive and dynamic imaging of biological tissues.

作者信息

Yang Peng, Liu Zhaoqi, Qin Siyao, Hu Jun, Yuan Songmei, Wang Zhong Lin, Chen Xiangyu

机构信息

Beijing Key Laboratory of Micro-Nano Energy and Sensor, Center for High-Entropy Energy and Systems, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 101400, P. R. China.

School of Nanoscience and Technology, University of Chinese Academy of Sciences, 100049 Beijing, China.

出版信息

Sci Adv. 2024 Dec 20;10(51):eadr9139. doi: 10.1126/sciadv.adr9139.

Abstract

Tissue imaging is usually captured by hospital-based nuclear magnetic resonance. Here, we present a wearable triboelectric impedance tomography (TIT) system for noninvasive imaging of various biological tissues. The imaging mechanism relies on the obtained impedance information from the different soft human tissues. A high-precision signal source is designed on the basis of a composite triboelectric nanogenerator, which exhibits a minimal total harmonic distortion of 0.03% and a peak output signal-to-noise ratio up to 120 decibels. The current density injected into human skin is around 79.58 milliamperes per square meter, far below the safety threshold for medical devices. The TIT system achieves time-resolved tomography of human limbs' soft tissues, and many appealing functions can be realized by using this wearable system, including the observation of muscle movement, the motion intention recognition, and the identification of pathological changes of soft tissue. Hence, this TIT system with excellent biocompatibility can be integrated with various devices, such as medical-assistive exoskeletons and smart protective suit.

摘要

组织成像通常由医院的核磁共振设备获取。在此,我们展示了一种用于对各种生物组织进行无创成像的可穿戴摩擦电阻抗断层扫描(TIT)系统。成像机制依赖于从人体不同软组织获取的阻抗信息。基于复合摩擦纳米发电机设计了一种高精度信号源,其总谐波失真最小为0.03%,峰值输出信噪比高达120分贝。注入人体皮肤的电流密度约为每平方米79.58毫安,远低于医疗设备的安全阈值。TIT系统实现了对人体四肢软组织的时间分辨断层扫描,使用这种可穿戴系统可以实现许多吸引人的功能,包括观察肌肉运动、运动意图识别以及软组织病理变化的识别。因此,这种具有优异生物相容性的TIT系统可以与各种设备集成,如医疗辅助外骨骼和智能防护服。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb38/11661438/ada3b20a095f/sciadv.adr9139-f1.jpg

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