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急诊胆囊切除术:危险因素及延误对择期手术患者的影响,一家三级医疗中心的5年经验

Emergency cholecystectomy: risk factors and impact of delay on electively booked patients, a 5-year experience of a tertiary care center.

作者信息

AlSaleh Nourah, Alaa Adeen Abdulqader Murad, Hetta Omar Esam, Alsiraihi Abdulaziz Abdullah, Bader Mahmoud Waleed Mahmoud, Aloufi Alwaleed Khalid, ALZahrani Farah Mohammed, Ramadan Majed, Ageel Amro Hasan, Alzahrani Mohammed

机构信息

Department of Surgery-Surgical Oncology, Ministry of National Guard Health Affairs, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

King Abdullah International Medical Research Centre, National Guard Health Affairs, Riyadh, Saudi Arabia.

出版信息

BMC Surg. 2024 Dec 20;24(1):396. doi: 10.1186/s12893-024-02694-8.

Abstract

BACKGROUND

Gallstone disease is one of the most resource-intensive surgical conditions. Despite the significant burden of emergency cholecystectomy on healthcare system, there is lack of research assessing the risk factors predisposing scheduled elective cholecystectomy patients to emergency surgery. Characterization of patients with gallstones helps to prioritize delivery of health care to avoid urgent surgery. The objective of the present study is to analyze risk factors associated with emergency cholecystectomy and assess the impact of delay on electively scheduled patients.

METHODS

This retrospective cohort study at a tertiary care center in Jeddah, Saudi Arabia, between January 2018 and June 2022. Net total of 823 patients.The study has collected data retrospectively from an electronic health record system. The data were entered and coded in excel sheet. All statistical tests were 2-sided and were conducted using SAS statistical software version 9.4 (SAS Institute Inc. Cary, NC).

RESULTS

A total of 823 patients met the inclusion criteria and enrolled in the analysis. Among them, 129 patients (15.67%) underwent emergency cholecystectomy, while 694 patients (84.33%) underwent elective cholecystectomy. The waiting time in days was significantly longer for patients undergoing emergency cholecystectomy (mean of 362 days) compared to those undergoing elective cholecystectomy (mean of 305 days). Patients with more than two previous ED visits were over five times more likely to undergo emergency cholecystectomy compared to those who had never visited the ED previously (p-value < 0.0001) Moreover, patients diagnosed with acute cholecystitis and pancreatitis were more likely to undergo emergency cholecystectomy compared to those not diagnosed with these conditions (p-value < 0.0001; p-value 0.02).

CONCLUSION

Analysis of risk factors and delay in patients with gallstones scheduled for elective cholecystectomy demonstrates that long waiting times, severity of the initial visit setting, Hemolytic anemia, and male gender were significantly related to emergency cholecystectomy. Independent risk factors for emergency cholecystectomy were frequency of ED visits, acute cholecystitis, pancreatitis, and CBD stone. Patients with these risk factors should be given priority on the waiting list to avoid emergency surgery. Future research is required to design a scoring system or specific criteria for elective patients at risk of developing acute cholecystitis.

摘要

背景

胆结石疾病是资源消耗最为严重的外科病症之一。尽管急诊胆囊切除术给医疗系统带来了沉重负担,但缺乏针对将择期胆囊切除术患者推向急诊手术的危险因素的研究。对胆结石患者的特征进行描述有助于优化医疗服务的提供,以避免紧急手术。本研究的目的是分析与急诊胆囊切除术相关的危险因素,并评估延迟对择期安排患者的影响。

方法

这是一项在沙特阿拉伯吉达一家三级医疗中心进行的回顾性队列研究,时间跨度为2018年1月至2022年6月。共有823例患者。该研究从电子健康记录系统中回顾性收集数据。数据录入并编码到Excel表格中。所有统计检验均为双侧检验,使用SAS统计软件9.4版(SAS Institute Inc.,北卡罗来纳州卡里)进行。

结果

共有823例患者符合纳入标准并纳入分析。其中,129例患者(15.67%)接受了急诊胆囊切除术,而694例患者(84.33%)接受了择期胆囊切除术。与接受择期胆囊切除术的患者(平均305天)相比,接受急诊胆囊切除术的患者等待天数明显更长(平均362天)。与从未去过急诊科的患者相比,之前去过急诊科超过两次的患者接受急诊胆囊切除术的可能性高出五倍多(p值<0.0001)。此外,与未被诊断出患有这些疾病的患者相比,被诊断出患有急性胆囊炎和胰腺炎的患者更有可能接受急诊胆囊切除术(p值<0.0001;p值0.02)。

结论

对计划进行择期胆囊切除术的胆结石患者的危险因素和延迟情况进行分析表明,等待时间长、初次就诊时的病情严重程度、溶血性贫血和男性性别与急诊胆囊切除术显著相关。急诊胆囊切除术的独立危险因素是急诊科就诊频率、急性胆囊炎、胰腺炎和胆总管结石。具有这些危险因素的患者应在等待名单上优先处理,以避免紧急手术。未来需要开展研究,为有发展为急性胆囊炎风险的择期患者设计一个评分系统或具体标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5df1/11662557/198fba54b009/12893_2024_2694_Fig1_HTML.jpg

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