Murakami Keiko, Nakadate Misako, Obara Taku, Aizawa Misato, Takahashi Ippei, Ishikuro Mami, Noda Aoi, Ohseto Hisashi, Iwama Noriyuki, Saito Masatoshi, Takachi Ribeka, Sugawara Shiori, Yonezawa Yudai, Yamashita Takahiro, Suzuki Shigenori, Ishihara Junko, Yamamoto Masayuki, Kuriyama Shinichi
Tohoku Medical Megabank Organization, Tohoku University.
Graduate School of Environmental Health, Azabu University.
J Epidemiol. 2024 Dec 21;35(7):305-12. doi: 10.2188/jea.JE20240293.
The Tohoku Medical Megabank Project has initiated the Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study) including genomic and omics investigations, and conducted a self-administered food frequency questionnaire with the response option "constitutionally unable to eat or drink it" for individual food items (TMM-FFQ) for pregnant women. This study evaluated the validity of the TMM-FFQ among pregnant women.
Participants comprised 122 pregnant women aged ≥20 years residing in Miyagi Prefecture who completed weighed food records (WFRs) for 3 days as reference intake and the TMM-FFQ during mid-pregnancy. Correlations between nutrient or food group intakes based on the WFR and the TMM-FFQ were calculated using Spearman's rank correlation coefficients (CCs), adjusting for energy intake and correcting for random within-individual variation of WFR. Cross-classification was also conducted according to quintiles using the WFR and TMM-FFQ data.
The percentages of participants who chose the "constitutionally unable to eat or drink it" option were >3% for seven food and drink items. CCs were >0.30 for 31 nutrients; the median across energy and 44 nutrients was 0.41. CCs were >0.30 for 14 food groups; the median across 20 food groups was 0.35. The median percentages of cross-classification into exact plus adjacent quintiles and extreme quintiles were 63.1% and 3.3% for energy and nutrients and 61.9% and 4.1% for food groups, respectively.
The validity of the TMM-FFQ compared with the WFR was reasonable for certain nutrients and food groups among pregnant women in the TMM BirThree Cohort Study.
东北医学综合研究机构发起了出生及三代队列研究（TMM BirThree队列研究），其中包括基因组和组学调查，并针对孕妇开展了一份自填式食物频率问卷，该问卷针对每种食物设有“体质上无法食用或饮用”这一回答选项（TMM-FFQ）。本研究评估了TMM-FFQ在孕妇中的有效性。
研究对象包括122名居住在宫城县、年龄≥20岁的孕妇，她们在孕期中期完成了3天的称重食物记录（WFRs）作为参考摄入量，并完成了TMM-FFQ。基于WFR和TMM-FFQ计算营养素或食物组摄入量之间的相关性，采用Spearman等级相关系数（CCs），对能量摄入进行调整，并校正WFR个体内的随机变异。还使用WFR和TMM-FFQ数据根据五分位数进行交叉分类。
七种食品和饮料中选择“体质上无法食用或饮用”选项的参与者比例>3%。31种营养素的CCs>0.30；能量和44种营养素的中位数为0.41。14个食物组的CCs>0.30；20个食物组的中位数为0.35。能量和营养素精确加相邻五分位数及极端五分位数交叉分类的中位数百分比分别为63.1%和3.3%，食物组分别为61.9%和4.1%。
在TMM BirThree队列研究中，对于孕妇的某些营养素和食物组，与WFR相比，TMM-FFQ的有效性是合理的。
