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传统骨肉瘤的最新进展

Update on Conventional Osteosarcoma.

作者信息

Teixeira Luiz Eduardo Moreira, Guedes Alex, Nakagawa Suely Akiko, Fonseca Karine Corrêa, Lima Eduardo Ribeiro

机构信息

Departamento do Aparelho Locomotor, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.

Grupo de Oncologia Ortopédica, Hospital Santa Izabel, Santa Casa de Misericórdia da Bahia, Salvador, BA, Brasil.

出版信息

Rev Bras Ortop (Sao Paulo). 2024 Jan 29;59(6):e815-e820. doi: 10.1055/s-0043-1771483. eCollection 2024 Dec.

Abstract

Conventional osteosarcoma is a high-grade malignant tumor characterized by the production of osteoid matrix by malignant osteoblasts. It typically affects the long bones of children and adolescents. Treatment includes systemic chemotherapy and a local surgical approach with wide resection. Recent advances in oncology concepts, imaging, surgical planning, and cancer treatment protocols allow for improved survival and a higher limb preservation rate. This paper addresses the current status regarding the incidence, pathology, treatment, and prognosis of conventional high-grade osteosarcoma.

摘要

传统骨肉瘤是一种高级别恶性肿瘤,其特征是恶性成骨细胞产生类骨质基质。它通常影响儿童和青少年的长骨。治疗方法包括全身化疗和采用广泛切除的局部手术方法。肿瘤学概念、影像学、手术规划和癌症治疗方案的最新进展提高了生存率并提高了保肢率。本文阐述了传统高级别骨肉瘤在发病率、病理学、治疗和预后方面的现状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/135b/11663062/75377c64bd11/10-1055-s-0043-1771483-i2200218en-1.jpg

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