Hassanin Sondos, Katira Arnav, Hardcastle Nicola
Dermatology, Sheffield Children's Hospital, Sheffield, GBR.
Cureus. 2024 Dec 19;16(12):e76017. doi: 10.7759/cureus.76017. eCollection 2024 Dec.
Bullous pemphigoid (BP) is a rare autoimmune blistering disease characterised by autoantibodies against basal skin membrane antigens. Although the condition's aetiology remains unclear, recent cases have raised suspicions of an association with immunisation. In this study, we present a case of BP onset in a four-month-old infant following routine vaccination. The infant with BP responded well to systemic therapy. This case emphasises the requirement for further investigation into the potential link between BP and vaccination.
大疱性类天疱疮(BP)是一种罕见的自身免疫性水疱病,其特征是针对皮肤基底膜抗原产生自身抗体。尽管该病的病因尚不清楚,但最近的病例引发了人们对其与免疫接种之间关联的怀疑。在本研究中,我们报告了一例4个月大婴儿在常规疫苗接种后发生BP的病例。该患有BP的婴儿对全身治疗反应良好。本病例强调了进一步调查BP与疫苗接种之间潜在联系的必要性。