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在美国有慢性消耗病病例报告地区的野猪(Sus scrofa)中朊病毒的检测

Detection of Prions in Wild Pigs (Sus scrofa) from Areas with Reported Chronic Wasting Disease Cases, United States.

作者信息

Soto Paulina, Bravo-Risi Francisca, Benavente Rebeca, Stimming Tucker H, Bodenchuk Michael J, Whitley Patrick, Turnage Clint, Spraker Terry R, Greenlee Justin, Telling Glenn, Malmberg Jennifer, Gidlewski Thomas, Nichols Tracy, Brown Vienna R, Morales Rodrigo

出版信息

Emerg Infect Dis. 2025 Jan;31(1):168-173. doi: 10.3201/eid3101.240401.

Abstract

Using a prion amplification assay, we identified prions in tissues from wild pigs (Sus scrofa) living in areas of the United States with variable chronic wasting disease (CWD) epidemiology. Our findings indicate that scavenging swine could play a role in disseminating CWD and could therefore influence its epidemiology, geographic distribution, and interspecies spread.

摘要

通过朊病毒扩增检测,我们在美国慢性消耗病(CWD)流行病学情况各异的地区,从野猪(Sus scrofa)组织中鉴定出了朊病毒。我们的研究结果表明,食腐猪可能在传播CWD中发挥作用,因此可能影响其流行病学、地理分布和种间传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0b3/11682794/bcc349e85cb3/24-0401-F1.jpg

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