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骨组织工程的一条新途径:基于聚合物的3D打印磁性支架(对[具体文献1]和[具体文献2]研究的全面综述)

A new path in bone tissue engineering: polymer-based 3D-printed magnetic scaffolds (a comprehensive review of and studies).

作者信息

Safavi Atiyeh Sadat, Karbasi Saeed

机构信息

Department of Biomaterials and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Biomater Sci Polym Ed. 2024 Dec 23:1-21. doi: 10.1080/09205063.2024.2444077.

DOI:10.1080/09205063.2024.2444077
PMID:39715733
Abstract

Bone tissue engineering is a promising approach to address the increasing need for bone repair. Scaffolds play a crucial role in providing the structural framework for cell growth and differentiation. 3D printing offers precise control over scaffold design and fabrication. Polymers and inorganic compounds such as magnetic nanoparticles (MNPs) are used to create biocompatible and functional scaffolds. MNPs enhance mechanical properties, facilitate drug delivery, and enable the real-time monitoring of bone regeneration. This review highlights the potential of polymer-based 3D-printed magnetic scaffolds in advancing bone regenerative medicine.

摘要

骨组织工程是一种很有前景的方法,可满足日益增长的骨修复需求。支架在为细胞生长和分化提供结构框架方面起着至关重要的作用。3D打印能够精确控制支架的设计和制造。聚合物和无机化合物(如磁性纳米颗粒(MNPs))被用于制造生物相容性和功能性支架。MNPs可增强力学性能、促进药物递送并实现骨再生的实时监测。本综述强调了基于聚合物的3D打印磁性支架在推进骨再生医学方面的潜力。

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