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中国青少年失眠与自杀未遂之间的关联:一项前瞻性队列研究。

The association between insomnia and suicide attempts among Chinese adolescents: a prospective cohort study.

作者信息

Lu Yuanyuan, Liu Zeteng, Luo Xuerong, Song Lintong, Fan Tianqing, Huang Chunxiang, Shen Yanmei

机构信息

Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.

Shantou University Mental Health Center, Shantou University Medical College, Shantou, China.

出版信息

BMC Psychol. 2024 Dec 24;12(1):777. doi: 10.1186/s40359-024-02273-9.

Abstract

OBJECTIVE

This study aimed to investigate a range of insomnia-related factors, including difficulty with sleep induction, nocturnal awakenings, early awakenings, total sleep time, overall sleep quality, well-being, functioning, and daytime drowsiness, to determine which variables were significantly associated with subsequent adolescent suicide attempts.

METHOD

A total of 782 students aged 11-16 years old from one middle school in Changsha, China completed the survey at baseline and 6 months follow-up with a prospective cohort design. The binary logistic regression models were used to analyze the associations between insomnia variables and suicide attempts during the 6 months follow-up.

RESULTS

The new incidence rate of suicide attempts was 4.60% (36/782) at 6-month follow-up. Insomnia was a significant predictor of incident suicide attempts (OR = 6.00; 95%CI, 2.47-14.60). After adjusting for age, gender, nationality, stress, anxiety and depression, insomnia was found to predict suicide attempts only among female (OR = 4.28; 95%CI, 1.41-12.98) and only nocturnal sleep disruption was significantly associated with an increased risk of suicide attempts (OR = 2.74; 95%CI, 1.32-5.71).

CONCLUSIONS

Nocturnal sleep disruption are independently associated with increased risk of suicide attempts. Intervention for nocturnal sleep disruption may be important for early identification as well as prevention of adolescent suicide, especially among adolescent girls.

摘要

目的

本研究旨在调查一系列与失眠相关的因素,包括入睡困难、夜间觉醒、早醒、总睡眠时间、整体睡眠质量、幸福感、功能状态和日间嗜睡,以确定哪些变量与青少年随后的自杀企图显著相关。

方法

采用前瞻性队列设计,对来自中国长沙一所中学的782名11 - 16岁学生在基线和6个月随访时进行调查。采用二元逻辑回归模型分析随访6个月期间失眠变量与自杀企图之间的关联。

结果

6个月随访时自杀企图的新发发生率为4.60%(36/782)。失眠是自杀企图事件的显著预测因素(比值比[OR]=6.00;95%置信区间[CI],2.47 - 14.60)。在调整年龄、性别、国籍、压力、焦虑和抑郁因素后,发现失眠仅在女性中可预测自杀企图(OR = 4.28;95%CI,1.41 - 12.98),且仅夜间睡眠中断与自杀企图风险增加显著相关(OR = 2.74;95%CI,1.32 - 5.71)。

结论

夜间睡眠中断与自杀企图风险增加独立相关。对夜间睡眠中断进行干预对于青少年自杀的早期识别和预防可能很重要,尤其是在青少年女性中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b131/11669201/ee1268e24823/40359_2024_2273_Fig1_HTML.jpg

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