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绝经后女性子宫畸胎瘤的综合诊断与治疗方法:病例研究及文献综述

Comprehensive diagnostic and therapeutic approaches to uterine teratoma in postmenopausal women: a case study and review.

作者信息

Pan Wenwei, Lan Jun, Tang Zihao, Li Taikang, Ma Xinping

机构信息

Department of Obstetrics and Gynecology, Dongguan Maternal and Child Health Care Hospital, Dongguan, China.

Dongguan Maternal and Child Health Care Hospital, Dongguan Key Laboratory of Female Reproductive Health, Dongguan, China.

出版信息

Front Oncol. 2024 Dec 11;14:1458187. doi: 10.3389/fonc.2024.1458187. eCollection 2024.

Abstract

BACKGROUND AND OBJECTIVE

Uterine teratomas are extremely rare in postmenopausal women and pose significant challenges in diagnosis and treatment. This study reports a case of a 54-year-old postmenopausal woman diagnosed with a uterine teratoma during a routine gynecological ultrasound. The study aims to explore the diagnosis and treatment of uterine teratomas in postmenopausal women through detailed imaging assessment and hysteroscopy surgery, aiming to enhance the understanding of this rare uterine tumor and improve patient treatment outcomes and quality of life.

METHODS

This study utilized hysteroscopic surgery to excise a mass initially suspected to be a uterine fibroid and performed pathological analysis. The analysis revealed the presence of fat and hair, confirming the diagnosis of a mature benign uterine teratoma. Additionally, the study includes a literature review summarizing the clinical characteristics, diagnostic methods, and treatment strategies for uterine teratomas.

RESULTS

Hysteroscopic surgery effectively identified and removed the complex uterine teratoma. Pathological analysis confirmed the teratoma contained various mature tissues, including neural tissue, bone, and cartilage. Comparative analysis of imaging features with surgical outcomes helped propose more precise diagnostic criteria and treatment guidelines.

CONCLUSION

Hysteroscopy surgery plays a crucial role in diagnosing uterine teratomas in postmenopausal women and showcases its advantages of minimal trauma and quick recovery in treatment. In addition, the literature review emphasizes the diagnostic challenges of uterine teratomas in clinical practice, particularly in expanding clinical awareness of the differences between premenopausal and postmenopausal presentations. It also summarizes the diagnostic and treatment strategies for rare uterine masses, contributing to the improved recognition of these rare cases.

摘要

背景与目的

子宫畸胎瘤在绝经后女性中极为罕见,在诊断和治疗方面面临重大挑战。本研究报告了一例54岁绝经后女性,在常规妇科超声检查中被诊断为子宫畸胎瘤。该研究旨在通过详细的影像学评估和宫腔镜手术,探讨绝经后女性子宫畸胎瘤的诊断和治疗方法,以加深对这种罕见子宫肿瘤的认识,提高患者的治疗效果和生活质量。

方法

本研究采用宫腔镜手术切除最初怀疑为子宫肌瘤的肿块,并进行病理分析。分析发现肿块内存在脂肪和毛发,确诊为成熟的良性子宫畸胎瘤。此外,该研究还包括文献综述,总结了子宫畸胎瘤的临床特征、诊断方法和治疗策略。

结果

宫腔镜手术有效地识别并切除了复杂的子宫畸胎瘤。病理分析证实畸胎瘤包含各种成熟组织,包括神经组织、骨骼和软骨。对影像学特征与手术结果的对比分析有助于提出更精确的诊断标准和治疗指南。

结论

宫腔镜手术在绝经后女性子宫畸胎瘤的诊断中起着关键作用,并显示出其在治疗中创伤小、恢复快的优势。此外,文献综述强调了子宫畸胎瘤在临床实践中的诊断挑战,特别是在扩大对绝经前和绝经后表现差异的临床认识方面。它还总结了罕见子宫肿块的诊断和治疗策略,有助于提高对这些罕见病例的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/497f/11668656/2668e60dc1be/fonc-14-1458187-g001.jpg

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