Devine P, Ucci A A
Hum Pathol. 1985 Jan;16(1):92-4. doi: 10.1016/s0046-8177(85)80219-7.
The case of a biliary cystadenoma containing foci of cystadenocarcinoma is reported, along with the first electron microscopic description of this lesion. Both neoplastic and congenital origins have been implicated in the pathogenesis of biliary cystadenomas. In this case hamartomatous bile ducts were found, supporting a congenital origin for at least some biliary cystadenomas. Careful pathologic evaluation is emphasized since malignant degeneration can be detected only after thorough sectioning.
本文报道了一例含有囊腺癌灶的胆管囊腺瘤病例，并首次对该病变进行了电子显微镜描述。胆管囊腺瘤的发病机制涉及肿瘤性起源和先天性起源。在该病例中发现了错构瘤样胆管，支持至少部分胆管囊腺瘤的先天性起源。强调要进行仔细的病理评估，因为只有在全面切片后才能检测到恶性变。
