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约旦北部酒渣鼻的人口统计学和临床特征:一项为期10年的大学医院回顾性研究。

Demographic and clinical features of rosacea in North Jordan: a 10-year university hospital retrospective study.

作者信息

Alshiyab Diala, Ba-Shammakh Saleh A, Bani Bakr Alaa, Abu-Hussein Mohammad, Al-Fakih Abdulqudos, Alawneh Sarah, Alhuneafat Leen, Heis Leen, Al-Qarqaz Firas

机构信息

Department of Dermatology, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Department of General Surgery, Ministry of Health, Amman, Jordan.

出版信息

Ann Med. 2025 Dec;57(1):2445775. doi: 10.1080/07853890.2024.2445775. Epub 2024 Dec 26.

DOI:10.1080/07853890.2024.2445775
PMID:39726294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11703501/
Abstract

BACKGROUND/OBJECTIVES: This study aims to investigate the demographic and clinical characteristics of rosacea within the North Jordan population, focusing on Fitzpatrick skin types III and IV. The intent is to address gaps in dermatological research concerning ethnic and racial variations in rosacea's presentation and impact.

METHODS

We conducted a retrospective cohort analysis at the dermatology department of King Abdullah University Hospital, North Jordan, reviewing medical records of patients diagnosed with rosacea from January 2013 to December 2023. Data collection focused on demographics, rosacea subtypes and environmental factors exacerbating the condition. Statistical analysis utilized Jamovi and GraphPad Prism software.

RESULTS

The study included 610 patients, revealing a rosacea prevalence of 1.5% within the hospital's catchment area. Most patients were female (84.4%), with a median age of 44. The majority had Fitzpatrick skin types III and IV. The erythematotelangiectatic subtype was most common (73.6%), followed by papulopustular (23.4%) and phymatous (3%). Environmental triggers like sun exposure and temperature changes were nearly universally reported as exacerbating factors.

CONCLUSIONS

Rosacea shows significant gender disparities and is influenced by environmental factors. The study underscores the need for targeted research and treatment strategies that consider ethnic and racial variations, along with gender-specific presentations of the disease.

摘要

背景/目的:本研究旨在调查约旦北部人群中酒渣鼻的人口统计学和临床特征,重点关注Fitzpatrick III型和IV型皮肤。目的是填补皮肤病学研究中关于酒渣鼻表现和影响的种族和民族差异方面的空白。

方法

我们在约旦北部阿卜杜拉国王大学医院皮肤科进行了一项回顾性队列分析,回顾了2013年1月至2023年12月期间被诊断为酒渣鼻的患者的病历。数据收集集中在人口统计学、酒渣鼻亚型和加重病情的环境因素上。统计分析使用了Jamovi和GraphPad Prism软件。

结果

该研究纳入了610名患者,显示该医院服务区域内酒渣鼻患病率为1.5%。大多数患者为女性(84.4%),中位年龄为44岁。大多数患者为Fitzpatrick III型和IV型皮肤。红斑毛细血管扩张型最为常见(73.6%),其次是丘疹脓疱型(23.4%)和鼻赘型(3%)。几乎所有患者都报告日晒和温度变化等环境诱因是加重因素。

结论

酒渣鼻存在显著的性别差异,并受环境因素影响。该研究强调需要开展有针对性的研究和治疗策略,考虑种族和民族差异以及该疾病的性别特异性表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d62/11703501/08163375f2ba/IANN_A_2445775_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d62/11703501/08163375f2ba/IANN_A_2445775_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d62/11703501/08163375f2ba/IANN_A_2445775_F0001_C.jpg

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Treatment strategies, including antibiotics, to target the immune component of rosacea.针对酒渣鼻的免疫成分的治疗策略,包括抗生素。
Expert Rev Clin Immunol. 2022 Dec;18(12):1239-1251. doi: 10.1080/1744666X.2022.2128334. Epub 2022 Sep 27.
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Improving Rosacea Outcomes in Skin of Color Patients: A Review on the Nuances in the Treatment and the Use of Cleansers and Moisturizers.
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J Drugs Dermatol. 2022 Jun 1;21(6):574-580. doi: 10.36849/JDD.6838.
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Assessment of Frequency of Rosacea Subtypes in Patients With Rosacea: A Systematic Review and Meta-analysis.评估玫瑰痤疮患者各亚型的频率:系统评价和荟萃分析。
JAMA Dermatol. 2022 Jun 1;158(6):617-625. doi: 10.1001/jamadermatol.2022.0526.
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Prevalence, clinical characteristics and health-related quality of life of rosacea in Chinese adolescents: a population-based study.中国青少年酒渣鼻的患病率、临床特征及健康相关生活质量:一项基于人群的研究。
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