不同年龄酒渣鼻男性患者的临床特征差异：215例男性门诊患者的回顾性研究
Differences in the Clinical Characteristics of Male Patients With Different Ages of Rosacea: A Retrospective Study of 215 Male Outpatients.
作者信息
Huang Yuwei, Chen Siliang, Liu Xu, Du Dan, Jiang Xian
机构信息
Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.
Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
出版信息
J Cosmet Dermatol. 2025 Jan;24(1):e16620. doi: 10.1111/jocd.16620. Epub 2024 Oct 7.
BACKGROUND
Rosacea is more common in women and Caucasians, leading to little research on rosacea in Asian men. Additionally, there is limited research on the patients across different age groups.
AIMS
The aim of this study is to analyze and compare the characteristics of male patients of rosacea among different age groups.
METHODS
A retrospective analysis was conducted on 215 male patients with rosacea, investigating their characteristics, clinical symptoms, exacerbating factors, complications, psychological status, and treatment, as well as exploring factors influencing the early onset of male rosacea.
RESULTS
The patients were divided into three age groups (≤ 30 years, 31-44 years, and ≥ 45 years), with the study revealing an average age of 38.59 ± 13.13 years among the patients. The most common subtype of rosacea in men was erythematotelangiectatic rosacea (ETR), followed by phymatous rosacea (PhR). The main reported features included persistent erythema (87.4%) and telangiectasia (71.2%), predominantly affecting the nose (58.6%) and cheeks (56.3%). Twenty-six percent of patients reported concurrent skin diseases, with 14.0% reporting systemic diseases. Significant differences were observed among different age groups regarding family history, clinical features, lesion distribution, symptom severity, aggravating factors, presence of systemic diseases, and treatment preferences. Subjective skin typing, Fitzpatrick phototype, and positive family history were identified as factors influencing the age of onset of rosacea in men.
CONCLUSION
Male patients with rosacea exhibit distinct clinical characteristics, with a greater prevalence of nasal involvement and nasal lesions among male patients. Clinical features vary among different age groups, with patients aged ≥ 45 experiencing more complex and severe symptoms. Patients aged ≤ 30 may be more influenced by genetic factors and have higher treatment expectations.
背景
酒渣鼻在女性和白种人中更为常见，导致针对亚洲男性酒渣鼻的研究较少。此外，针对不同年龄组患者的研究也有限。
目的
本研究旨在分析和比较不同年龄组男性酒渣鼻患者的特征。
方法
对215例男性酒渣鼻患者进行回顾性分析，调查他们的特征、临床症状、加重因素、并发症、心理状态和治疗情况，并探讨影响男性酒渣鼻早期发病的因素。
结果
患者被分为三个年龄组（≤30岁、31 - 44岁和≥45岁），研究显示患者的平均年龄为38.59±13.13岁。男性酒渣鼻最常见的亚型是红斑毛细血管扩张型酒渣鼻（ETR），其次是肥大性酒渣鼻（PhR）。主要报告的特征包括持续性红斑（87.4%）和毛细血管扩张（71.2%），主要影响鼻子（58.6%）和脸颊（56.3%）。26%的患者报告有并发皮肤病，14.0%报告有全身性疾病。在家族史、临床特征、皮损分布、症状严重程度、加重因素、全身性疾病的存在以及治疗偏好等方面，不同年龄组之间存在显著差异。主观皮肤分型、菲茨帕特里克皮肤光型和阳性家族史被确定为影响男性酒渣鼻发病年龄的因素。
结论
男性酒渣鼻患者表现出独特的临床特征，男性患者中鼻受累和鼻部病变的患病率更高。不同年龄组的临床特征各不相同，≥45岁的患者症状更复杂、更严重。≤30岁的患者可能受遗传因素影响更大，对治疗的期望更高。
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