Zou Yanzheng, Lin Yihu, Qian Yili, Tao Luqiu, Tan Gao, Zhu Hongru, Pan Li, Liu Xiaoli, He Yu, Wang Wei
National Health Commission Key Laboratory of Parasitic Diseases Prevention and Control, Wuxi 214064, China.
Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology, Wuxi 214064, China.
Trop Med Infect Dis. 2024 Dec 3;9(12):295. doi: 10.3390/tropicalmed9120295.
To assess the burden of food-borne trematodiases in China from 1990 to 2021 and project the burden through 2035, data were captured from the Global Burden of Disease Study (GBD) 2021 datasets. The estimated prevalent food-borne trematodiase cases were 33.32 million (95% uncertainty interval (): 29.25-38.35 million) in China in 2021, contributing to 768,297.4 disability-adjusted life years (DALYs) (95% : 383,882.8-1,367,826.1). The number of prevalent cases and DALYs declined by 9.02% and 18.11%, and a downward decline was seen in age-standardized prevalence and DALY rates (estimated annual percentage change: -0.96% and -1.21%, respectively). A higher prevalence and DALY rates were observed among males than females, and the middle-aged group bore the highest burden, while the older population showed the most rapid increase in prevalent cases and DALY numbers. Projected DALY counts and rates remain stable through 2035 using the Bayesian age-period-cohort (BAPC) model. These findings demonstrate a decline in the burden of food-borne trematodiases in China from 1990 to 2021; however, the prevalence remained high, which contributed considerably to disability and premature death. Continued control efforts and targeted interventions are essential to further reducing the burden of food-borne trematodiases in China.
为评估1990年至2021年中国食源性吸虫病的负担，并预测到2035年的负担情况，我们从《2021年全球疾病负担研究》（GBD 2021）数据集中获取了数据。2021年，中国食源性吸虫病的估计流行病例为3332万例（95%不确定区间：2925万 - 3835万例），导致768297.4伤残调整生命年（DALYs）（95%：383882.8 - 1367826.1）。流行病例数和DALYs分别下降了9.02%和18.11%，年龄标准化患病率和DALY率也呈下降趋势（估计年变化百分比分别为 -0.96%和 -1.21%）。男性的患病率和DALY率高于女性，中年人群负担最重，而老年人群的流行病例数和DALY数增长最为迅速。使用贝叶斯年龄 - 时期 - 队列（BAPC）模型预测，到2035年DALY数和率将保持稳定。这些发现表明，1990年至2021年中国食源性吸虫病负担有所下降；然而，患病率仍然很高，这在很大程度上导致了残疾和过早死亡。持续的防控努力和有针对性的干预措施对于进一步减轻中国食源性吸虫病的负担至关重要。
