Annopawong Kornkamol, Sriyuttagrai Wararee, Chainakul Methaphon, Arjkongharn Niracha, Seresirikachorn Kasem, Kongsomboon Kittipong, Wanichwecharungruang Boonsong
Department of Ophthalmology, Rajavithi Hospital and College of Medicine, Rangsit University, Bangkok, Thailand.
School of Medicine, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Sci Rep. 2024 Dec 28;14(1):31026. doi: 10.1038/s41598-024-82246-5.
Relative anterior microphthalmos (RAM) is a rare ocular condition characterized by disproportionately small anterior segments but normal axial length (corneal diameter < 11 mm and axial length > 20 mm). This study aimed to determine the prevalence of RAM and its association with glaucoma utilizing IOL Master 700 data (Carl Zeiss Meditec, Jena, Germany). A retrospective analysis was conducted of the biometric parameters of 6,407 eyes, and 115 cases of RAM were identified. The incidence of glaucoma was assessed, together with the outcomes of cataract surgery in cases of RAM with glaucoma. RAM prevalence was 1.8%. RAM patients had a higher incidence of glaucoma (26.1%), notably of the angle-closure subtype. Cataract surgery significantly reduced intraocular pressure in cases of RAM with glaucoma; however, RAM patients experienced a higher rate of surgical complications. RAM poses clinical challenges due to its association with glaucoma and increased surgical risks. This study emphasizes the importance of advanced diagnostic tools such as the IOL Master in tailoring interventions to optimize patient outcomes.
相对性小眼球前段（RAM）是一种罕见的眼部疾病，其特征为前段不成比例地小，但眼轴长度正常（角膜直径<11毫米且眼轴长度>20毫米）。本研究旨在利用IOL Master 700数据（德国耶拿卡尔蔡司医疗技术公司）确定RAM的患病率及其与青光眼的关联。对6407只眼的生物测量参数进行了回顾性分析，识别出115例RAM病例。评估了青光眼的发病率以及RAM合并青光眼患者的白内障手术结果。RAM患病率为1.8%。RAM患者青光眼发病率较高（26.1%），尤其是闭角型亚型。白内障手术显著降低了RAM合并青光眼患者的眼压；然而，RAM患者手术并发症发生率较高。由于RAM与青光眼相关且手术风险增加，给临床带来了挑战。本研究强调了先进诊断工具如IOL Master在制定干预措施以优化患者预后方面的重要性。
