Jaouhari Mustapha, El Harrak Chaimae, Bentayeb Farida, El Merabet Youssef
Laboratory of Electronic Systems, Mechanical, and Energy Information Processing, MA.
Laboratory of high energy physics, modeling, and simulation, MA.
Br Ir Orthopt J. 2024 Dec 27;20(1):264-270. doi: 10.22599/bioj.382. eCollection 2024.
To investigate if the type of unilateral amblyopia can impact the improvement of visual acuity in amblyopic eyes during a longitudinal interventional study involving standard occlusion therapy in children.
A longitudinal and interventional study of 91 children, aged 3-9 years (6.12 ± 1.879) with amblyopia was undertaken. Amblyopia was unilateral and caused by either strabismus, anisometropia, or both. Amblyopia was divided into three levels of severity mild, moderate, and severe. Children underwent amblyopia treatment with standard occlusion therapy and were followed monthly, for eight visits.
A significant improvement in visual acuity was observed in all assessment visits across the three types of amblyopia, with a mean improvement of (0.30 ± 0.184) LogMAR. Specifically, anisometropic amblyopia with (0.28 ± 0.18) LogMAR, strabismic amblyopia (0.31 ± 0.18) LogMAR, and mixed amblyopia (0.31 ± 0.18) LogMAR. No significant differences were found between the improvement in visual acuity during the eight control visits and the types of amblyopia (r = 0.174, p = 0.182). However, a significant correlation was observed within all groups in the mean improvement in visual acuity and the severity level (r = 0.712, p = 0.034).
Amblyopia types do not appear to significantly affect the improvement in visual acuity; however, the initial severity of amblyopia may be a key factor influencing the degree of visual recovery achieved with occlusion therapy.
在一项针对儿童标准遮盖疗法的纵向干预研究中，调查单侧弱视的类型是否会影响弱视眼视力的改善情况。
对91名年龄在3至9岁（平均6.12±1.879岁）的弱视儿童进行了纵向干预研究。弱视均为单侧，由斜视、屈光参差或两者共同引起。弱视分为轻度、中度和重度三个严重程度级别。儿童接受标准遮盖疗法进行弱视治疗，并每月随访一次，共随访8次。
在三种类型的弱视患者的所有评估访视中，视力均有显著改善，平均改善幅度为（0.30±0.184）LogMAR。具体而言，屈光参差性弱视的改善幅度为（0.28±0.18）LogMAR，斜视性弱视为（0.31±0.18）LogMAR，混合性弱视为（0.31±0.18）LogMAR。在8次对照访视期间，视力改善情况与弱视类型之间未发现显著差异（r = 0.174，p = 0.182）。然而，在所有组中，视力平均改善情况与严重程度级别之间存在显著相关性（r = 0.712，p = 0.034）。
弱视类型似乎不会显著影响视力的改善；然而，弱视的初始严重程度可能是影响遮盖疗法所实现的视力恢复程度的关键因素。
