Li Yuhan, Xu Chuangyi, Liao Yifan, Chen Xiao, Chen Jiang, Yang Fan, Gao Mingyuan
College of Engineering and Technology, Southwest University, Chongqing 400716, China.
School of Traffic & Transportation Engineering, Central South University, Changsha 410000, China.
Biomicrofluidics. 2024 Dec 24;18(6):061303. doi: 10.1063/5.0227248. eCollection 2024 Dec.
Bio-microfluidic technologies offer promising applications in diagnostics and therapy, yet they face significant technical challenges, particularly in the need for external power sources, which limits their practicality and user-friendliness. Recent advancements have explored innovative methods utilizing body fluids, motion, and heat to power these devices, addressing the power supply issue effectively. Among these, body-motion and body-heat-powered systems stand out for their potential to create self-sustaining, wearable, and implantable devices. In this Perspective, we focus on the principles and applications of hydrovoltaic cells, biofuel cells, and piezoelectric and triboelectric nanogenerators. Recent strides in energy conversion efficiency, coupled with the development of biocompatible and durable materials, are driving innovation in bio-integrated electronics. Integration with bio-microfluidic platforms further enhances the linkage to the human body and the potential of these devices for personalized healthcare applications. Ongoing research into these areas promises to deliver sustainable and user-friendly solutions for continuous monitoring, diagnostics, and therapy, potentially revolutionizing the landscape of healthcare delivery.
生物微流控技术在诊断和治疗方面有着广阔的应用前景，但它们面临着重大的技术挑战，尤其是在需要外部电源方面，这限制了它们的实用性和用户友好性。最近的进展探索了利用体液、运动和热量为这些设备供电的创新方法，有效地解决了电源问题。其中，身体运动和身体热量驱动的系统因其创造自持、可穿戴和可植入设备的潜力而脱颖而出。在这篇综述中，我们重点关注水力发电电池、生物燃料电池以及压电和摩擦电纳米发电机的原理和应用。能量转换效率的最新进展，加上生物相容性和耐用材料的开发，正在推动生物集成电子学的创新。与生物微流控平台的整合进一步加强了与人体的联系，以及这些设备在个性化医疗应用中的潜力。对这些领域的持续研究有望为连续监测、诊断和治疗提供可持续且用户友好的解决方案，可能会彻底改变医疗保健服务的格局。
