The influence of rhizosphere microbial diversity on the accumulation of active compounds in farmed .

Rhizosphere microorganisms are important factors affecting herb quality and secondary metabolite accumulation. In this study, we investigated the diversity of rhizosphere microbial communities (bacteria and fungi) and their correlations with soil physicochemical properties and active compounds of (baicalin, oroxindin, baicalein, wogonin, and oroxylin A) from cultivated with three different origins high-throughput sequencing and correlation analysis to further clarify the role of soil factors in the accumulation of the active compounds of . The results are summarized as follows. A total of 28 dominant bacterial genera, such as , , and , and 42 dominant fungal genera, such as , and , were detected. The soil microbial communities associated with cultivated were very diverse, but there were some differences in the relative abundances of microbial taxa. Correlation analysis revealed that the bacterial genera , and and the fungal genera , and were positively or negatively correlated with each active component of and were important genera affecting the accumulation of the active compounds of and correlated with soil physiochemistry to different degrees. These results suggest that rhizosphere microorganisms may play a role in the accumulation of active compounds in medicinal plants and provide a scientific basis for guiding the cultivation of , developing biofertilizers, and improving the quality of medicinal materials.