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The unexplored potential of exosomes in the muscle-brain axis.

作者信息

Caruso Bavisotto Celeste, Bucchieri Fabio, Cappello Francesco

机构信息

Section of Human Anatomy, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.

Euro-Mediterranean Institute of Science and Technology, 90139 Palermo, Italy.

出版信息

Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2420766121. doi: 10.1073/pnas.2420766121. Epub 2024 Dec 31.

DOI:10.1073/pnas.2420766121
PMID:39739797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11725874/
Abstract
摘要

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本文引用的文献

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Nanovesicular Mediation of the Gut-Brain Axis by Probiotics: Insights into Irritable Bowel Syndrome.益生菌对肠-脑轴的纳米囊泡介导作用：对肠易激综合征的见解
Biology (Basel). 2024 Apr 25;13(5):296. doi: 10.3390/biology13050296.
2
Neuronal innervation regulates the secretion of neurotrophic myokines and exosomes from skeletal muscle.神经元支配调节骨骼肌神经营养性肌因子和外泌体的分泌。
Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2313590121. doi: 10.1073/pnas.2313590121. Epub 2024 Apr 29.
3
Intestinal Epithelial Cell Exosome Launches IL-1β-Mediated Neuron Injury in Sepsis-Associated Encephalopathy.肠道上皮细胞外泌体引发脓毒症相关性脑病中 IL-1β 介导的神经元损伤。
Front Cell Infect Microbiol. 2022 Jan 17;11:783049. doi: 10.3389/fcimb.2021.783049. eCollection 2021.
4
Bacterial Extracellular Vesicles and the Gut-Microbiota Brain Axis: Emerging Roles in Communication and Potential as Therapeutics.细菌细胞外囊泡与肠道微生物群-脑轴：在通讯中的新兴作用及作为治疗手段的潜力
Adv Biol (Weinh). 2021 Jul;5(7):e2000540. doi: 10.1002/adbi.202000540. Epub 2021 Apr 15.
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Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier Transcytosis.肿瘤细胞外囊泡穿透完整的血脑屏障 胞吞作用。
ACS Nano. 2019 Dec 24;13(12):13853-13865. doi: 10.1021/acsnano.9b04397. Epub 2019 Sep 10.
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Biological properties of extracellular vesicles and their physiological functions.细胞外囊泡的生物学特性及其生理功能。
J Extracell Vesicles. 2015 May 14;4:27066. doi: 10.3402/jev.v4.27066. eCollection 2015.
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Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation.细胞外囊泡介导的造血系统与大脑之间的遗传信息传递，以响应炎症。
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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes.通过系统注射靶向 exosomes 将 siRNA 递送到小鼠大脑。
Nat Biotechnol. 2011 Apr;29(4):341-5. doi: 10.1038/nbt.1807. Epub 2011 Mar 20.