Yarbrough Courtney R, Cooper Hannah L F, Beane Stephanie, Haardörfer Regine, Ibragimov Umed, Haley Danielle F, Linton Sabriya, Landes Sarah, Lewis Rashunda, Sionean Catlainn, Cummings Janet R
Department of Health Policy and Management, Rollins School of Public Health at Emory University, Atlanta, GA, USA.
Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health at Emory University, Atlanta, GA, USA.
Subst Use Misuse. 2025;60(4):531-541. doi: 10.1080/10826084.2024.2440365. Epub 2024 Dec 31.
People who inject drugs (PWID) are especially vulnerable to harms from opioid use disorder (OUD). Medications for OUD (MOUD) effectively reduce overdose and infectious disease transmission risks.
We investigate whether state Medicaid coverage for methadone and buprenorphine is related to past-year MOUD use among PWID using cross-sectional, multilevel analyses with individual-level data on PWID from the Centers for Disease Control and Prevention's 2018 National HIV Behavioral Surveillance. The sample included 8,142 PWID aged 18-64 who reported daily opioid use from 22 U.S. metropolitan areas. Our outcome was any self-reported MOUD use in the past 12 months. Exposures were state Medicaid coverage and prior authorization requirements for methadone and buprenorphine. We interacted these exposures with PWID race/ethnicity, insurance status, and spatial access to treatment and harm reduction resources.
Compared with PWID in states without Medicaid methadone coverage, odds of past-year MOUD use were 73% (<0.05) higher among PWID in states with methadone coverage requiring prior authorization and 80% (<0.05) higher among PWID in states with coverage without prior authorization. Insured PWID were twice as likely to report MOUD use than uninsured PWID, with no statistically significant differences between Medicaid versus other insurance. Medicaid prior authorization requirements for buprenorphine were not significantly associated with MOUD use. Non-Hispanic Black PWID were significantly less likely to use MOUD than non-Hispanic White and Hispanic PWID.
State Medicaid methadone coverage was strongly associated with higher odds that PWID utilized MOUD, suggesting that expanding methadone insurance coverage could improve MOUD treatment in a vulnerable population.
注射毒品者(PWID)特别容易受到阿片类药物使用障碍(OUD)的伤害。用于治疗OUD的药物(MOUD)能有效降低过量用药和传染病传播风险。
我们利用横断面、多层次分析以及来自疾病控制与预防中心2018年全国HIV行为监测的PWID个体层面数据,调查各州医疗补助计划对美沙酮和丁丙诺啡的覆盖情况是否与PWID过去一年使用MOUD相关。样本包括来自美国22个大都市地区的8142名年龄在18 - 64岁且报告每日使用阿片类药物的PWID。我们的结果是在过去12个月内自我报告的任何MOUD使用情况。暴露因素是各州医疗补助计划的覆盖情况以及美沙酮和丁丙诺啡的预先授权要求。我们将这些暴露因素与PWID的种族/民族、保险状况以及获得治疗和减少伤害资源的空间可及性进行了交互分析。
与没有医疗补助计划美沙酮覆盖的州的PWID相比,有预先授权要求的美沙酮覆盖州的PWID过去一年使用MOUD的几率高73%(<0.05),无预先授权覆盖州的PWID过去一年使用MOUD的几率高80%(<0.05)。有保险的PWID报告使用MOUD的可能性是无保险PWID的两倍,医疗补助与其他保险之间无统计学显著差异。丁丙诺啡的医疗补助预先授权要求与MOUD使用无显著关联。非西班牙裔黑人PWID使用MOUD的可能性显著低于非西班牙裔白人和西班牙裔PWID。
州医疗补助计划的美沙酮覆盖与PWID使用MOUD的几率较高密切相关,这表明扩大美沙酮保险覆盖范围可以改善弱势群体的MOUD治疗。