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通过实施针对开处方者的决策支持工具降低住院患者低血糖发生率

Inpatient Hypoglycemic Rate Reduction Through the Implementation of Prescriber Targeted Decision Support Tools.

作者信息

Odom Jessica, Goldstein Rebecca

机构信息

Prisma Health, Pharmacy, 701 Grove Road, Greenville, SC, 29605, USA.

出版信息

Curr Diab Rep. 2025 Jan 4;25(1):15. doi: 10.1007/s11892-024-01571-1.

DOI:10.1007/s11892-024-01571-1
PMID:39754663
Abstract

PURPOSE OF REVIEW

Hypoglycemia has been shown to increase mortality and length of hospital stay and is now reportable to the Centers for Medicare and Medicaid Services as a quality measure. The purpose of this article is to review clinical decision support (CDS) tools designed to reduce inpatient hypoglycemic events.

RECENT FINDINGS

CDS tools such as order set development, medication alerts, and data visibility have all been shown to be valuable tools in improving glycemic performance. This is especially true for hyperglycemic events with mixed results in hypoglycemia prevention. CDS solutions may be targeted directly to healthcare professionals or to specialty diabetes management teams to reduce hypoglycemia. Not all organizations have the financial resources to develop a diabetes management team so non-interruptive alerts may serve as an important tool to alert health care professionals of individuals with additional risk factors for the development of hypoglycemia. CDS can provide a mechanism to reduce the risk of hypoglycemia in hospitalized individuals. Although new research is promising, more studies are needed to determine future directions including the impact and feasibility of continuous glucose monitoring and predictive models to improve overall glycemic performance.

摘要

综述目的

低血糖已被证明会增加死亡率和住院时间,现在作为一项质量指标需向医疗保险和医疗补助服务中心报告。本文旨在综述旨在减少住院患者低血糖事件的临床决策支持(CDS)工具。

最新发现

诸如医嘱集开发、用药警示和数据可视化等CDS工具,均已被证明是改善血糖控制情况的宝贵工具。对于高血糖事件尤其如此,而在预防低血糖方面结果不一。CDS解决方案可直接针对医疗保健专业人员或专业糖尿病管理团队,以降低低血糖风险。并非所有机构都有财力组建糖尿病管理团队,因此非干扰性警示可能是提醒医疗保健专业人员注意有发生低血糖额外风险因素个体的重要工具。CDS可提供一种机制,降低住院患者发生低血糖的风险。尽管新研究很有前景,但仍需要更多研究来确定未来方向,包括持续血糖监测的影响和可行性以及改善整体血糖控制情况的预测模型。

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本文引用的文献

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Clinical Decision Support: Moving Beyond Interruptive "Pop-up" Alerts.临床决策支持:超越干扰性的“弹出式”警报
Mayo Clin Proc. 2023 Sep;98(9):1275-1279. doi: 10.1016/j.mayocp.2023.05.025.
2
Clinical Decision Support for Glycemic Management Reduces Hospital Length of Stay.临床决策支持用于血糖管理可减少住院时间。
Diabetes Care. 2022 Nov 1;45(11):2526-2534. doi: 10.2337/dc21-0829.
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Continuous Glucose Monitoring-Guided Insulin Administration in Hospitalized Patients With Diabetes: A Randomized Clinical Trial.住院糖尿病患者的连续血糖监测指导下的胰岛素给药:一项随机临床试验。
Diabetes Care. 2022 Oct 1;45(10):2369-2375. doi: 10.2337/dc22-0716.
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Implementation of an Electronic Health Record Integrated Clinical Pathway Improves Adherence to COVID-19 Hospital Care Guidelines.实施电子病历集成临床路径可提高对 COVID-19 住院治疗指南的依从性。
Am J Med Qual. 2022;37(4):335-341. doi: 10.1097/JMQ.0000000000000036. Epub 2022 Jan 11.
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Reliability of Inpatient CGM: Comparison to Standard of Care.住院患者连续血糖监测的可靠性:与常规护理的比较。
J Diabetes Sci Technol. 2023 Mar;17(2):329-335. doi: 10.1177/19322968211062168. Epub 2021 Dec 15.
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Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial.电子健康记录急性肾损伤警报:多中心、随机临床试验。
BMJ. 2021 Jan 18;372:m4786. doi: 10.1136/bmj.m4786.
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Reducing Inpatient Hypoglycemia in the General Wards Using Real-time Continuous Glucose Monitoring: The Glucose Telemetry System, a Randomized Clinical Trial.使用实时连续血糖监测减少普通病房住院患者低血糖症:血糖遥测系统,一项随机临床试验。
Diabetes Care. 2020 Nov;43(11):2736-2743. doi: 10.2337/dc20-0840. Epub 2020 Aug 5.
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Hypoglycemia Associated with Antibiotics Alone and in Combination with Sulfonylureas and Meglitinides: An Epidemiologic Surveillance Study of the FDA Adverse Event Reporting System (FAERS).与抗生素单独使用以及与磺酰脲类药物和米格列醇联合使用相关的低血糖症:FDA 不良事件报告系统(FAERS)的一项流行病学监测研究。
Drug Saf. 2020 Apr;43(4):363-369. doi: 10.1007/s40264-019-00901-7.
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IMPLEMENTATION OF AN ELECTRONIC DASHBOARD WITH A REMOTE MANAGEMENT SYSTEM TO IMPROVE GLYCEMIC MANAGEMENT AMONG HOSPITALIZED ADULTS.实施电子仪表盘与远程管理系统以改善住院成人的血糖管理。
Endocr Pract. 2020 Feb;26(2):179-191. doi: 10.4158/EP-2019-0264. Epub 2019 Sep 26.
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Early Intervention for Diabetes in Medical and Surgical Inpatients Decreases Hyperglycemia and Hospital-Acquired Infections: A Cluster Randomized Trial.住院患者糖尿病的早期干预可降低高血糖和医院获得性感染:一项整群随机试验。
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