Izumi Kakeru, Tsuyuki Yuzo, Harada Kazuki
Sanritsu Zelkova Veterinary Laboratory, Tokyo, Japan.
Laboratory of Veterinary Internal Medicine, Tottori University, Tottori, Japan.
J Vet Med Sci. 2025 Mar 1;87(3):269-272. doi: 10.1292/jvms.24-0452. Epub 2025 Jan 3.
We investigated the distribution and antimicrobial resistance of 120 Staphylococcus felis isolates from feline patients in Japan, mainly from the urinary tract (28.3%), abscesses (23.3%), ears (22.5%), and nasal cavity (10.8%). The distribution of S. felis differed from those of previous studies in Japan and other countries. Antimicrobial susceptibility testing revealed a relatively high resistance to penicillin (PEN, 33.3%), followed by erythromycin (ERY, 15.8%), clindamycin (CLI, 13.3%), and levofloxacin (5.0%). However, oxacillin resistance was not detected. Notably, 11/120 (9.2%)S. felis isolates exhibited multidrug resistance, i.e., resistance to more than three classes of drugs, which mainly consisted of PEN-ERY-CLI resistance phenotypes. This is the first investigation on antimicrobial-resistant S. felis isolates from feline patients in Japan.
我们调查了来自日本猫科动物患者的120株猫葡萄球菌分离株的分布及耐药性，这些分离株主要来自泌尿道（28.3%）、脓肿（23.3%）、耳部（22.5%）和鼻腔（10.8%）。猫葡萄球菌的分布与日本及其他国家以往的研究不同。药敏试验显示，该菌对青霉素（PEN，33.3%）的耐药性相对较高，其次是红霉素（ERY，15.8%）、克林霉素（CLI，13.3%）和左氧氟沙星（5.0%）。然而，未检测到对苯唑西林的耐药性。值得注意的是，120株猫葡萄球菌分离株中有11株（9.2%）表现出多重耐药性，即对三类以上药物耐药，主要为PEN-ERY-CLI耐药表型。这是日本首次对猫科动物患者的耐抗菌药物猫葡萄球菌分离株进行的调查。
