Miao Nae-Fang, Hsieh Chia-Jung, Li Pei-Shan
Post-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical University, Taipei 110301, Taiwan.
School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei 112303, Taiwan.
Healthcare (Basel). 2024 Dec 20;12(24):2568. doi: 10.3390/healthcare12242568.
This study explores depression changes and influencing factors in middle-aged and older individuals, focusing on different cognitive function states. This cohort study uses panel data from seven waves of the nationally representative Taiwan Longitudinal Study on Aging (1996-2015) with 2344 participants aged 50 or above. Data analysis was conducted from 25 January 2023 to 4 May 2023. Multivariate logistic regression analyzed three trajectories: maintained mood, progressive depression, and consistent depression. Protective factors for progressive depression included self-health perception, exercise, family satisfaction, and financial well being, while risk factors were chronic diseases, pain, substance use, and daily activity limitations. Cognitive function emerged as a significant protective factor, while pain exhibited the highest risk. In the cognitive dysfunction group, only social participation showed notable differences. Progressive and consistent depression in middle-aged and older people have aroused concern. In addition to necessary protection and risk factors, special attention should be paid to the risks posed by the level of pain. Addressing pain as a crucial risk factor is essential, particularly for middle-aged and older people with cognitive impairment and depression, necessitating targeted support.
本研究探讨了中老年人的抑郁变化及其影响因素，重点关注不同的认知功能状态。这项队列研究使用了来自具有全国代表性的台湾老年纵向研究七轮的面板数据（1996 - 2015年），共有2344名50岁及以上的参与者。数据分析于2023年1月25日至2023年5月4日进行。多变量逻辑回归分析了三种轨迹：情绪维持、渐进性抑郁和持续性抑郁。渐进性抑郁的保护因素包括自我健康认知、运动、家庭满意度和财务状况良好，而风险因素则是慢性病、疼痛、物质使用和日常活动受限。认知功能是一个显著的保护因素，而疼痛表现出最高的风险。在认知功能障碍组中，只有社会参与存在显著差异。中老年人的渐进性和持续性抑郁已引起关注。除了必要的保护因素和风险因素外，还应特别关注疼痛程度带来的风险。将疼痛作为关键风险因素加以应对至关重要，尤其是对于有认知障碍和抑郁的中老年人，需要有针对性的支持。
