Yin Yao, Wang Xueke, Feng Tingyong
Faculty of Psychology, Southwest University, Chongqing 400715, China.
Key Laboratory of Cognition and Personality, Ministry of Education, Southwest University, Chongqing 400715, China.
Brain Sci. 2024 Dec 9;14(12):1237. doi: 10.3390/brainsci14121237.
: Noninvasive brain stimulation (NIBS) is a promising complementary treatment for attention-deficit/hyperactivity disorder (ADHD). However, its efficacy varies due to diverse participant profiles and methodologies. This meta-analysis, registered with PROSPERO (CRD42023457269), seeks to assess NIBS efficacy in improving cognitive deficits and clinical symptoms in individuals with ADHD. : We systematically searched five databases (October 2024) for randomized controlled trials focusing on cognitive functions and clinical symptoms in individuals meeting the DSM/ICD criteria for ADHD. A meta-analytical synthesis was conducted using RevMan 5.4.1. : Meta-analyses found significant improvement in inhibitory control, working memory, and inattention in active transcranial direct current stimulation (tDCS) groups compared with sham groups. Conversely, repetitive transcranial magnetic stimulation (rTMS) did not demonstrate significant therapeutic benefits for ADHD symptoms. Additionally, four transcranial random noise stimulation (tRNS) and three transcranial alternating current stimulation (tACS) studies demonstrated promising improvements in executive functions and the alleviation of ADHD symptoms. : The findings from this meta-analysis highlight NIBS as a promising adjunctive therapy for managing ADHD, advancing both theoretical knowledge and practical treatment options in this field.
非侵入性脑刺激（NIBS）是一种很有前景的注意力缺陷多动障碍（ADHD）辅助治疗方法。然而，由于参与者特征和方法的不同，其疗效也有所差异。这项在PROSPERO（CRD42023457269）注册的荟萃分析旨在评估NIBS对改善ADHD患者认知缺陷和临床症状的疗效。
我们系统检索了五个数据库（截至2024年10月），以查找针对符合ADHD的DSM/ICD标准的个体的认知功能和临床症状的随机对照试验。使用RevMan 5.4.1进行荟萃分析综合。
荟萃分析发现，与假刺激组相比，主动经颅直流电刺激（tDCS）组在抑制控制、工作记忆和注意力不集中方面有显著改善。相反，重复经颅磁刺激（rTMS）对ADHD症状未显示出显著的治疗益处。此外，四项经颅随机噪声刺激（tRNS）和三项经颅交流电刺激（tACS）研究表明，在执行功能和ADHD症状缓解方面有有前景的改善。
这项荟萃分析的结果突出了NIBS作为一种有前景的ADHD管理辅助治疗方法，推动了该领域的理论知识和实际治疗选择。
