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新西兰青少年对发育起源健康与疾病(DOHaD)概念的理解:对知识、干预窗口期和信息可及性的定性探索

Understanding DOHaD Concepts Among New Zealand Adolescents: A Qualitative Exploration of Knowledge, Intervention Windows, and Information Accessibility.

作者信息

Tohi Melenaite, Tu'akoi Siobhan, Vickers Mark H

机构信息

Liggins Institute, University of Auckland, Auckland 1023, New Zealand.

Maurice Wilkins Centre, University of Auckland, Auckland 1023, New Zealand.

出版信息

Int J Environ Res Public Health. 2024 Nov 25;21(12):1556. doi: 10.3390/ijerph21121556.

DOI:10.3390/ijerph21121556
PMID:39767398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11675382/
Abstract

The Developmental Origins of Health and Disease (DOHaD) framework has highlighted the role of maternal and paternal health on disease risk in offspring and across generations. Although adolescence is increasingly recognised as a key DOHaD window where interventions may have the greatest impact in breaking the cycle of non-communicable diseases, data around the recognition of this concept in adolescents remain limited. Previous work by our group found that the understanding of DOHaD-related concepts among adolescents in New Zealand was low, including some adolescents showing disagreement with key DOHaD concepts. This qualitative study aimed to explore DOHaD perspectives and understandings among a group of adolescents who responded to the survey using semi-structured focus groups and interviews ( = 12). Four core themes were identified: 1. knowledge of DOHaD and DOHaD-related terminology; 2. understanding different life course windows for DOHaD interventions; 3. recognising that DOHaD-related information needs to be accessible for adolescents; and 4. the importance of developing context-specific resources for adolescents. Adolescents in this study indicated that they had not heard of DOHaD or related terminology. Although the majority recognised that there were many important life stages for potential interventions, there was a strong emphasis on adolescence as a key window of opportunity. Adolescents suggested that more could be done in schools to help promote awareness and understanding of DOHaD-related concepts during the later years of schooling. The development of future resources needs to be contextually specific for adolescents to ensure increased uptake of information during this important developmental window.

摘要

健康与疾病的发育起源(DOHaD)框架突出了母体和父体健康对后代及跨代疾病风险的作用。尽管青春期越来越被视为一个关键的DOHaD窗口期,在此期间进行干预可能对打破非传染性疾病循环产生最大影响,但关于青少年对这一概念的认知数据仍然有限。我们团队之前的研究发现,新西兰青少年对与DOHaD相关概念的理解程度较低,包括一些青少年对DOHaD的关键概念表示不同意。这项定性研究旨在通过半结构化焦点小组和访谈(n = 12),探索一组对调查做出回应的青少年对DOHaD的看法和理解。确定了四个核心主题:1. 对DOHaD及与DOHaD相关术语的了解;2. 理解DOHaD干预的不同生命历程窗口期;3. 认识到青少年需要能够获取与DOHaD相关的信息;4. 为青少年开发因地制宜资源的重要性。本研究中的青少年表示他们没有听说过DOHaD或相关术语。尽管大多数人认识到有许多重要的生命阶段可进行潜在干预,但他们强烈强调青春期是一个关键的机遇窗口。青少年建议在学校后期可以做更多工作,以帮助提高对与DOHaD相关概念的认识和理解。未来资源的开发需要针对青少年因地制宜,以确保在这个重要的发育窗口期增加信息的接受度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/11675382/5e7ab5c024f2/ijerph-21-01556-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/11675382/5e7ab5c024f2/ijerph-21-01556-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/940f/11675382/5e7ab5c024f2/ijerph-21-01556-g001.jpg

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本文引用的文献

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J R Soc N Z. 2022 Apr 20;52(4):450-471. doi: 10.1080/03036758.2022.2060266. eCollection 2022.
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A systematic review exploring evidence for adolescent understanding of concepts related to the developmental origins of health and disease.一项系统综述,探索青少年对与健康和疾病的发育起源相关概念的理解证据。
J Dev Orig Health Dis. 2023 Dec;14(6):755-762. doi: 10.1017/S2040174423000442. Epub 2024 Jan 23.
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Paternal programming of fetoplacental and offspring metabolic disorders.
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Placenta. 2023 Sep 26;141:71-77. doi: 10.1016/j.placenta.2023.06.009. Epub 2023 Jun 18.
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Lancet. 2023 May 20;401(10389):1707-1719. doi: 10.1016/S0140-6736(23)00522-6. Epub 2023 May 8.
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Understanding the importance of the early-life period for adult health: a systematic review.理解生命早期对成年健康的重要性:系统综述。
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Realising transformative change in adolescent health and wellbeing: a second Lancet Commission.实现青少年健康与福祉的变革性变化:第二届《柳叶刀》委员会
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