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肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)女性患者中慢性疼痛和疲劳严重程度与天气及空气污染之间的关联

Association Between Chronic Pain and Fatigue Severity with Weather and Air Pollution Among Females with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

作者信息

Jones Chloe Lisette, Haskin Olivia, Younger Jarred Wayne

机构信息

Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.

出版信息

Int J Environ Res Public Health. 2024 Nov 26;21(12):1560. doi: 10.3390/ijerph21121560.

DOI:10.3390/ijerph21121560
PMID:39767402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11675267/
Abstract

Weather and air quality conditions have been anecdotally reported to be related to symptom fluctuations in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), but this has never been empirically investigated. This exploratory study aims to examine the effects of weather and air quality on daily fluctuations of chronic pain and fatigue in women with ME/CFS. In an intensive longitudinal design, 58 participants with ME/CFS provided daily pain and fatigue ratings for an average of 61 days. Daily weather and air quality data were obtained from the National Oceanic and Atmospheric Administration and the US Environmental Protection Agency for the Birmingham, AL area. Linear mixed models revealed a significant relationship between days with more severe pain and worse Air Quality Indices (AQI, < 0.001), lower wind speeds ( = 0.009), greater particulate matter ( = 0.037), and lower carbon monoxide ( = 0.004), sulfur dioxide ( = 0.003), and ozone levels ( = 0.015). Greater fatigue was associated with more particulates ( = 0.023) and lower barometric pressure ( = 0.048). These results suggest that air quality and weather can have small effects on ME/CFS symptom severity.

摘要

据传闻,天气和空气质量状况与肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)的症状波动有关,但从未进行过实证研究。这项探索性研究旨在考察天气和空气质量对ME/CFS女性患者慢性疼痛和疲劳每日波动的影响。在一项密集纵向设计中,58名ME/CFS患者平均61天每天提供疼痛和疲劳评分。每日天气和空气质量数据来自美国国家海洋和大气管理局以及美国环境保护局阿拉巴马州伯明翰地区的数据。线性混合模型显示,疼痛更严重的日子与更差的空气质量指数(AQI,<0.001)、更低的风速(=0.009)、更多的颗粒物(=0.037)以及更低的一氧化碳(=0.004)、二氧化硫(=0.003)和臭氧水平(=0.015)之间存在显著关系。更大的疲劳感与更多的颗粒物(=0.023)和更低的气压(=0.048)有关。这些结果表明,空气质量和天气对ME/CFS症状严重程度可能有微小影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef9/11675267/df92108fb784/ijerph-21-01560-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef9/11675267/df92108fb784/ijerph-21-01560-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef9/11675267/df92108fb784/ijerph-21-01560-g001.jpg

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