Liu Tai-Ti, Hong Kai-Siang, Yang Tsung-Shi
Department of Food Science, Yuanpei University of Medical Technology, No. 306 Yuanpei Street, Hsinchu 30015, Taiwan.
Department of Cosmeceutics, China Medical University, No. 100, Sec. 1, Jingmao Rd., Beitun Dist., Taichung 406040, Taiwan.
Molecules. 2024 Dec 13;29(24):5890. doi: 10.3390/molecules29245890.
This research aimed to modify polysaccharides extracted from the edible mushroom with gallic acid (GA) and to complex them with zinc ions. The functionalities of the modified polysaccharides (TFPs) were investigated. Regarding antioxidant activity, TFP-GA demonstrated effective scavenging activity against DPPH radicals, nitric oxide, and hydrogen peroxide. Additionally, TFP-GA exhibited superior reducing ability toward Fe and enhanced chelating activity toward Fe compared to unmodified TFP. Notably, the TFP-GA conjugate outperformed GA in Fe-chelating activity. In terms of antimicrobial activity, the TFP-GA-Zn complex showed significantly improved antimicrobial effectiveness against and compared to TFP-GA.
本研究旨在用没食子酸（GA）修饰从食用菌中提取的多糖，并使其与锌离子络合。对修饰后的多糖（TFPs）的功能进行了研究。在抗氧化活性方面，TFP-GA对DPPH自由基、一氧化氮和过氧化氢表现出有效的清除活性。此外，与未修饰的TFP相比，TFP-GA对铁具有更强的还原能力，并增强了对铁的螯合活性。值得注意的是，TFP-GA缀合物在铁螯合活性方面优于GA。在抗菌活性方面，与TFP-GA相比，TFP-GA-Zn络合物对[具体菌种1]和[具体菌种2]表现出显著提高的抗菌效果。
