Kamali Selin G, Durmazpinar Parla M, Turkaydin Dilek, Ovecoglu Hesna S
Department of Endodontics, Faculty of Dentistry, Marmara University, Istanbul, Turkey,
Department of Endodontics, Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Am J Dent. 2024 Dec;37(6):303-306.
To investigate the relationship between type 1 diabetes mellitus (T1-DM) and apical periodontitis (AP). The periapical and endodontic conditions of T1-DM individuals were compared with healthy people.
T1-DM subjects aged 18-45 with good glycemic control (HbA1c < 7) were included in this research. Individuals without systemic disease, twice as many as diabetic patients, were selected as the control group by matching them in terms of age and gender. The subjects' periapical and endodontic statuses were determined by assessing their existing digital panoramic radiographs.
This study included 226 subjects with T1-DM, 101 males and 125 females (30.78 ± 8.59 years). For the control group, 452 subjects without systemic disease, 224 males and 228 females (30.26 ± 8.64 years) were selected. The mean number of teeth in the control group was significantly higher than in the T1-DM group (P = 0.001). However, no significant difference was found between the T1-DM and control groups in terms of endodontic and periapical conditions (P > 0.05). Bivariate logistic regression analysis revealed a positive association between T1-DM and the number of teeth with AP only (P = 0.001; OR = 1.476). There was no association between T1-DM and endodontic conditions or other periapical health-related variables.
T1-DM patients lost more teeth than the control individuals. As the number of teeth with AP increased, individuals were more likely to be in the T1-DM group. Healthcare professionals should inform patients with Type 1 diabetes about oral health for a better quality of life.
探讨1型糖尿病（T1-DM）与根尖周炎（AP）之间的关系。将T1-DM患者的根尖周和牙髓状况与健康人群进行比较。
本研究纳入了年龄在18-45岁、血糖控制良好（糖化血红蛋白<7）的T1-DM患者。选择无全身性疾病且数量为糖尿病患者两倍的个体作为对照组，在年龄和性别方面进行匹配。通过评估现有的数字化全景X线片来确定受试者的根尖周和牙髓状况。
本研究纳入了226例T1-DM患者，其中男性101例，女性125例（年龄30.78±8.59岁）。对照组选择了452例无全身性疾病的个体，其中男性224例，女性228例（年龄30.26±8.64岁）。对照组的平均牙齿数量显著高于T1-DM组（P = 0.001）。然而，T1-DM组与对照组在牙髓和根尖周状况方面无显著差异（P>0.05）。二元逻辑回归分析显示，T1-DM仅与患有AP的牙齿数量呈正相关（P = 0.001；比值比=1.476）。T1-DM与牙髓状况或其他与根尖周健康相关的变量之间无关联。
T1-DM患者比对照组患者牙齿缺失更多。随着患有AP的牙齿数量增加，个体更有可能属于T1-DM组。医护人员应告知1型糖尿病患者有关口腔健康的知识，以提高生活质量。
