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向柬埔寨森林地区居民分发包含新型病媒控制工具的“森林包”的成本及后勤工作。

The costs and logistics of distributing 'forest packs' containing novel vector control tools to forest-exposed populations in Cambodia.

作者信息

Yukich Joshua, Doum Dyna, McIver David J, Richardson Jason H, Sovannaroth Siv, Lobo Neil F, Tatarsky Allison

机构信息

School of Public Health and Tropical Medicine, Tulane University, New Orleans, USA.

Health Forefront Organization, Phnom Penh, Cambodia.

出版信息

Malar J. 2025 Jan 7;24(1):2. doi: 10.1186/s12936-024-05237-x.

DOI:10.1186/s12936-024-05237-x
PMID:39773468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11705909/
Abstract

BACKGROUND

Malaria incidence in the Greater Mekong Subregion has been on the decline, and most remaining malaria risk in the region is concentrated among hard-to-reach populations, especially those with exposure to forested areas. New vector control tools focused on outdoor protection in forest settings are needed for these populations.

METHODS

The delivery of a 'forest pack' containing a volatile pyrethroid spatial repellent (VPSR), a topical repellent, and pyrethroid treatment of clothing was evaluated in an operational study in Cambodia. Costs were collected using micro-costing approaches and the cost of distribution for the 'forest pack' was estimated using standard economic evaluation approaches and examined in sensitivity analyses.

RESULTS

The cost per eligible person (the target population) per malaria season for the whole pack was estimated to be 138 USD, which was nearly entirely driven by the cost of the products.

CONCLUSIONS

Modifications to the 'forest pack' including adding a longer-lasting spatial repellent product or a reduced-cost topical repellent could significantly reduce the cost of pack distribution over the course of a malaria season.

摘要

背景

大湄公河次区域的疟疾发病率一直在下降,该区域剩余的大多数疟疾风险集中在难以到达的人群中,特别是那些接触森林地区的人群。这些人群需要专注于森林环境户外防护的新型病媒控制工具。

方法

在柬埔寨的一项实地研究中,对包含拟除虫菊酯挥发性空间驱避剂(VPSR)、局部驱避剂和衣物拟除虫菊酯处理的“森林套装”的发放情况进行了评估。使用微观成本核算方法收集成本,并使用标准经济评估方法估算“森林套装”的分发成本,并在敏感性分析中进行检验。

结果

整个套装每个疟疾季节每位符合条件的人(目标人群)的成本估计为138美元,这几乎完全由产品成本驱动。

结论

对“森林套装”进行改进,包括添加更长效的空间驱避产品或成本更低的局部驱避剂,可以在疟疾季节显著降低套装分发成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/11705909/fb961d34d8fa/12936_2024_5237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/11705909/5185b0b11e5c/12936_2024_5237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/11705909/fb961d34d8fa/12936_2024_5237_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/11705909/5185b0b11e5c/12936_2024_5237_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0226/11705909/fb961d34d8fa/12936_2024_5237_Fig2_HTML.jpg

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本文引用的文献

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Malar J. 2024 Dec 19;23(1):392. doi: 10.1186/s12936-024-05224-2.
2
The effect of novel mosquito bite prevention tools on Anopheles minimus landing and key secondary endpoints: semi-field evaluations in Thailand.新型防蚊叮咬工具对微小按蚊着陆及关键次要终点的影响:泰国的半田间评估
Malar J. 2024 Dec 18;23(1):387. doi: 10.1186/s12936-024-05188-3.
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Estimating the Size of Populations at High Risk of Malaria in 2 Operational Districts in Cambodia: Household-Based Survey.
估算柬埔寨 2 个运作地区疟疾高危人群规模:基于家庭的调查。
JMIR Public Health Surveill. 2024 Sep 27;10:e58584. doi: 10.2196/58584.
4
Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in Cambodia.现场评估一种挥发性拟除虫菊酯空间驱避剂和埃托芬肟处理过的衣物,以在柬埔寨户外防止森林疟疾媒介。
Sci Rep. 2024 Jul 29;14(1):17348. doi: 10.1038/s41598-024-67470-3.
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Inference for entomological semi-field experiments: Fitting a mathematical model assessing personal and community protection of vector-control interventions.昆虫学半野外实验推断:拟合评估蚊虫控制干预个人和社区保护效果的数学模型。
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