Stirrat Thomas, Martin Robert, Baek Gregorio, Thiru Shankar, Lakhani Dhairya, Umair Muhammad, Sayah Anousheh
Department of Radiology, Georgetown University, Washington, United States.
Department of Medicine, Inspira Medical Center, Mullica Hill, United States.
J Clin Imaging Sci. 2024 Dec 17;14:49. doi: 10.25259/JCIS_119_2024. eCollection 2024.
The realm of precision medicine, particularly its application within various sectors, shines notably in neuroradiology, where it leverages the advancements of three-dimensional (3D) printing technology. This synergy has significantly enhanced surgical planning, fostered the creation of tailor-made medical apparatus, bolstered medical pedagogy, and refined targeted therapeutic delivery. This review delves into the contemporary advancements and applications of 3D printing in neuroradiology, underscoring its pivotal role in refining surgical strategies, augmenting patient outcomes, and diminishing procedural risks. It further articulates the utility of 3D-printed anatomical models for enriched comprehension, simulation, and educational endeavors. In addition, it illuminates the horizon of bespoke medical devices and prosthetics, illustrating their utility in addressing specific cranial and spinal anomalies. This narrative extends to scrutinize how 3D printing underpins precision medicine by offering customized drug delivery mechanisms and therapies tailored to the patient's unique medical blueprint. It navigates through the inherent challenges of 3D printing, including the financial implications, the need for procedural standardization, and the assurance of quality. Prospective trajectories and burgeoning avenues, such as material and technological innovations, the confluence with artificial intelligence, and the broadening scope of 3D printing in neurosurgical applications, are explored. Despite existing hurdles, the fusion of 3D printing with neuroradiology heralds a transformative era in precision medicine, poised to elevate patient care standards and pioneer novel surgical paradigms.
精准医学领域，尤其是其在各个领域的应用，在神经放射学中表现显著，该领域利用三维（3D）打印技术的进步。这种协同作用显著改进了手术规划，促进了定制医疗设备的制造，加强了医学教学，并优化了靶向治疗递送。本文综述深入探讨了3D打印在神经放射学中的当代进展和应用，强调其在完善手术策略、提高患者预后以及降低手术风险方面的关键作用。它还阐述了3D打印解剖模型在丰富理解、模拟和教育活动方面的效用。此外，它还介绍了定制医疗设备和假肢的前景，说明了它们在解决特定颅面和脊柱异常方面的效用。这一论述还延伸至审视3D打印如何通过提供定制的药物递送机制和根据患者独特医疗蓝图量身定制的疗法来支撑精准医学。它探讨了3D打印所面临的固有挑战，包括财务影响、程序标准化的需求以及质量保证。还探索了前瞻性轨迹和新兴途径，如材料和技术创新、与人工智能的融合以及3D打印在神经外科应用中不断扩大的范围。尽管存在现有障碍，但3D打印与神经放射学的融合预示着精准医学的变革时代，有望提高患者护理标准并开创全新的手术模式。
