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3D 打印生物医学设备及其应用:最新技术、现有挑战和未来展望的综述。

3D printed biomedical devices and their applications: A review on state-of-the-art technologies, existing challenges, and future perspectives.

机构信息

Faculty of Mechanical Engineering, Silesian University of Technology, Konarskiego 18A, 44-100, Gliwice, Poland.

Faculty of Mechanical Engineering, Silesian University of Technology, Konarskiego 18A, 44-100, Gliwice, Poland.

出版信息

J Mech Behav Biomed Mater. 2023 Jul;143:105930. doi: 10.1016/j.jmbbm.2023.105930. Epub 2023 May 27.

Abstract

3D printing, also known as Additive manufacturing (AM), has emerged as a transformative technology with applications across various industries, including the medical sector. This review paper provides an overview of the current status of AM technology, its challenges, and its application in the medical industry. The paper covers the different types of AM technologies, such as fused deposition modeling, stereolithography, selective laser sintering, digital light processing, binder jetting, and electron beam melting, and their suitability for medical applications. The most commonly used biomedical materials in AM, such as plastic, metal, ceramic, composite, and bio-inks, are also viewed. The challenges of AM technology, such as material selection, accuracy, precision, regulatory compliance, cost and quality control, and standardization, are also discussed. The review also highlights the various applications of AM in the medical sector, including the production of patient-specific surgical guides, prosthetics, orthotics, and implants. Finally, the review highlights the Internet of Medical Things (IoMT) and artificial intelligence (AI) for regulatory frameworks and safety standards for 3D-printed biomedical devices. The review concludes that AM technology can transform the healthcare industry by enabling patients to access more personalized and reasonably priced treatment alternatives. Despite the challenges, integrating AI and IoMT with 3D printing technology is expected to play a vital role in the future of biomedical device applications, leading to further advancements and improvements in patient care. More research is needed to address the challenges and optimize its use for medical applications to utilize AM's potential in the medical industry fully.

摘要

3D 打印,也称为增材制造(AM),已经成为一种具有变革性的技术,在包括医疗领域在内的各个行业都有应用。本文综述了 AM 技术的现状、挑战及其在医疗行业的应用。本文涵盖了不同类型的 AM 技术,如熔融沉积建模、立体光刻、选择性激光烧结、数字光处理、粘结剂喷射和电子束熔化,以及它们在医疗应用中的适用性。还讨论了 AM 技术中使用的最常见的生物医学材料,如塑料、金属、陶瓷、复合材料和生物墨水。还讨论了 AM 技术的挑战,如材料选择、准确性、精度、法规遵从性、成本和质量控制以及标准化。本文还强调了 AM 在医疗领域的各种应用,包括制作患者特定的手术指南、假肢、矫形器和植入物。最后,本文强调了物联网(IoT)和人工智能(AI)在 3D 打印生物医学设备的监管框架和安全标准中的应用。本文综述得出结论,AM 技术可以通过使患者能够获得更个性化和合理价格的治疗选择来改变医疗保健行业。尽管存在挑战,但将 AI 和 IoT 与 3D 打印技术集成有望在生物医学设备应用的未来发挥重要作用,从而进一步提高患者护理水平。需要进一步的研究来解决挑战并优化其在医疗应用中的使用,以充分发挥 AM 在医疗行业的潜力。

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