Ma Weifeng, Guo Rui, Hu Wei
Department of Orthopaedic Surgery, The Bozhou Hospital Affiliated to Anhui Medical University, Bozhou, Anhui, China.
Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
World Neurosurg. 2025 Mar;195:123648. doi: 10.1016/j.wneu.2024.123648. Epub 2025 Feb 1.
Acute spinal cord injury causes severe motor and sensory dysfunction, significantly burdening individuals and society. This study uses bibliometric analysis to identify research trends and key areas, providing insights for future advancements in treatment.
Scientific publications on acute spinal cord injury were collected from PubMed and the Web of Science Core Collection between 2000 and 2022. Data were analyzed using Bibliometric, CiteSpace, and Bibliographic Item Co-occurrence Matrix Builder, with gCLUTO applied for co-word bicluster analysis based on MeSH term matrices.
Two thousand five hundred thirteen publications on acute spinal cord injury were published, with the number of articles increasing annually from 38 to 268. Spinal cord has emerged as the leading journal in this field, and the United States maintains its dominant position in global research impact. The University of Toronto ranks first among research institutions, with significant contributions from researchers such as Fehlings and Kwon. Research on acute spinal cord injury primarily focuses on 7 key areas: metabolism, pharmacology, surgical timing, rehabilitation, pathology, clinical predictors, and diagnostic imaging.
Our study reveals substantial growth in acute spinal cord injury research over the past 2 decades, emphasizing leading countries, researchers, institutions, and journals. Animal models remain pivotal in drug development for basic medicine and neuroscience. Consensus has been reached among experts regarding the timing of surgical intervention, while artificial intelligence and multidisciplinary approaches are emerging as promising avenues for comprehensive treatment. Additionally, ongoing research into spinal cord injury pathophysiology provides essential guidance for pharmacological and surgical treatments.
急性脊髓损伤会导致严重的运动和感觉功能障碍，给个人和社会带来沉重负担。本研究采用文献计量分析来确定研究趋势和关键领域，为未来治疗进展提供见解。
从2000年至2022年期间从PubMed和科学引文索引核心合集收集有关急性脊髓损伤的科学出版物。使用文献计量学、CiteSpace和文献共现矩阵构建器对数据进行分析，并应用gCLUTO基于医学主题词矩阵进行共词双聚类分析。
共发表了2513篇关于急性脊髓损伤的出版物，文章数量从38篇逐年增加到268篇。《脊髓》已成为该领域的领先期刊，美国在全球研究影响力方面保持主导地位。多伦多大学在研究机构中排名第一，费林斯和权等研究人员做出了重大贡献。急性脊髓损伤的研究主要集中在7个关键领域：代谢、药理学、手术时机、康复、病理学、临床预测指标和诊断成像。
我们的研究揭示了过去20年急性脊髓损伤研究的大幅增长，强调了领先国家、研究人员、机构和期刊。动物模型在基础医学和神经科学的药物开发中仍然至关重要。专家们已就手术干预的时机达成共识，而人工智能和多学科方法正成为综合治疗的有前景的途径。此外，对脊髓损伤病理生理学的持续研究为药物和手术治疗提供了重要指导。
