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外用类固醇的使用与处方模式:埃塞俄比亚德西综合专科医院的一项研究

Utilization and prescription patterns of topical steroids: a study at dessie comprehensive specialized hospital, Ethiopia.

作者信息

Mengesha Yohannes, Gebre Abay, Ejigu Yenesew Wudu

机构信息

Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

Arch Dermatol Res. 2025 Jan 9;317(1):213. doi: 10.1007/s00403-024-03733-3.

Abstract

BACKGROUND

Topical steroids are widely used in dermatology for their anti-inflammatory and immunosuppressive effects, but misuse can cause skin thinning and systemic issues. In Ethiopia, where skin conditions are common, understanding how topical steroids are prescribed and used is essential for ensuring their safe and effective use.

OBJECTIVE

The study aimed to assess topical steroids' prescription and utilization pattern in Dessie Comprehensive Specialized Hospital (DCSH) from February 1 to May 30, 2024.

METHODOLOGY

The study used a descriptive, cross-sectional design with a quantitative approach, analyzing data from 175 patient records on prescription and utilization patterns of topical steroids at DCSH. Participants were selected using a random sampling technique. Data were categorized and analyzed using Microsoft Excel 2010, with findings presented through descriptive statistics, including tables and figures.

RESULT

Eczematous dermatitis (31.49%) was the most common skin disease observed, followed by dermatophytosis (12.15%). Out of 304 drugs prescribed, averaging 1.73 per prescription, clobetasol (44.4%) and betamethasone (25.0%) were the most common topical corticosteroids. These steroids were primarily prescribed for eczema, dermatitis, pigmentary disorders, psoriasis, urticaria, and lichen planus. The commonly prescribed drugs were topical steroids 108[35.53%]. Generic names were used for 54.63% of the 108 topical steroids prescribed.

CONCLUSION

The study found that dermatitis and eczema are the most common skin conditions treated in dermatology clinics, with topical steroids being the main treatment. However, many prescriptions lacked details on the application site, treatment duration, and quantity. To improve safety and effectiveness, the study recommends community education, better dermatological services, and increased oversight in professional training.

摘要

背景

外用糖皮质激素因其抗炎和免疫抑制作用在皮肤科广泛应用,但滥用会导致皮肤变薄和全身性问题。在皮肤病常见的埃塞俄比亚,了解外用糖皮质激素的处方和使用情况对于确保其安全有效使用至关重要。

目的

本研究旨在评估2024年2月1日至5月30日德西综合专科医院(DCSH)外用糖皮质激素的处方和使用模式。

方法

本研究采用描述性横断面设计和定量方法,分析了DCSH 175份患者记录中关于外用糖皮质激素处方和使用模式的数据。采用随机抽样技术选取参与者。使用Microsoft Excel 2010对数据进行分类和分析,研究结果通过描述性统计呈现,包括表格和图表。

结果

观察到的最常见皮肤病是湿疹性皮炎(31.49%),其次是皮肤癣菌病(12.15%)。在开出的304种药物中,平均每张处方1.73种,氯倍他索(44.4%)和倍他米松(25.0%)是最常用的外用糖皮质激素。这些糖皮质激素主要用于治疗湿疹、皮炎、色素沉着紊乱、银屑病、荨麻疹和扁平苔藓。常用药物为外用糖皮质激素108种[35.53%]。在开出的108种外用糖皮质激素中,54.63%使用的是通用名。

结论

研究发现,皮炎和湿疹是皮肤科诊所治疗的最常见皮肤病,外用糖皮质激素是主要治疗药物。然而,许多处方缺乏关于应用部位、治疗持续时间和用量的详细信息。为提高安全性和有效性,研究建议开展社区教育、改善皮肤科服务并加强专业培训监督。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0638/11717826/77a1477e1ded/403_2024_3733_Fig1_HTML.jpg

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