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O-linked β-N-acetylglucosaminylation in lung cancer and beyond: A multidimensional perspective.

作者信息

Jiang Jinxiu, Huang Xiaochun, Feng Jianguo, Liu Li, Liu Yulin, Jia Jing

机构信息

Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China.

Anesthesiology and Critical Care Medicine Key Laboratory of Luzhou, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, China.

出版信息

Chin Med J (Engl). 2025 Feb 5;138(3):355-357. doi: 10.1097/CM9.0000000000003329. Epub 2024 Dec 31.

DOI:10.1097/CM9.0000000000003329
PMID:39787372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11771721/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7038/11771721/14fe7056d399/cm9-138-355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7038/11771721/14fe7056d399/cm9-138-355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7038/11771721/14fe7056d399/cm9-138-355-g001.jpg

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Nat Chem Biol. 2024 Jan;20(1):19-29. doi: 10.1038/s41589-023-01354-x. Epub 2023 Jun 12.
2
O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy.O-糖基化:一种重要的翻译后修饰,也是癌症治疗的潜在治疗靶点。
Mol Med. 2022 Sep 14;28(1):115. doi: 10.1186/s10020-022-00544-y.
3
GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvation.
与GFAT1相关的TAB1谷氨酰化可维持p38丝裂原活化蛋白激酶的激活,并在葡萄糖饥饿条件下促进肺癌细胞存活。
Cell Discov. 2022 Aug 9;8(1):77. doi: 10.1038/s41421-022-00423-0.
4
OGT as potential novel target: Structure, function and inhibitors.作为潜在新靶点的O-连接N-乙酰葡糖胺转移酶:结构、功能及抑制剂
Chem Biol Interact. 2022 Apr 25;357:109886. doi: 10.1016/j.cbi.2022.109886. Epub 2022 Mar 11.
5
Targeting PGM3 as a Novel Therapeutic Strategy in Co-Mutant Lung Cancer.靶向 PGM3 作为共突变肺癌的一种新的治疗策略。
Cells. 2022 Jan 5;11(1):176. doi: 10.3390/cells11010176.
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Neurosci Bull. 2022 Mar;38(3):263-274. doi: 10.1007/s12264-021-00776-8. Epub 2021 Nov 5.
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